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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 45 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of IRF4 Deregulation of MUM1/ IRF4 by chromosomal translocation in multiple myeloma. Previous work has demonstrated that the B- cell proliferation/ differentiation marker MUM1/ IRF4...( including colonic, lung, breast, and ovarian carcinomas). Expression of MUM1/ IRF4 selectively clusters... / Synonyms: IRF-4
Mus musculus
Gene: ... Disease relevance of Irf4 The critical function of IRF- 4 in TLR signaling in vivo is underscored by the observation that Irf4- deficient mice show hypersensitivity to DNA- induced shock, with elevated serum proinflammatory cytokine levels. After infection of IRF4 (-/-) mice with the protozoan parasite Leishmania major... / Synonyms: IRF-4
MeSH term: ... Gene context of Leukemia- Lymphoma, Adult T- Cell The expression of nuclear c- Rel and IRF- 4 occurs in the absence of Tax in primary ATLL and is associated with antiviral resistance....
Gallus gallus
Gene: ... Disease relevance of IRF4 The expression of IRF- 4 from retrovirus vectors morphologically..., and promoted their growth in soft agar. High impact information on IRF4 IRF- 10 is most closely related to IRF- 4 but differs in both its constitutive and inducible expression. The exogenous expression of IRF- 4...
MeSH term: ... Myeloma Deregulation of MUM1/ IRF4 by chromosomal translocation in multiple myeloma. Efficacy...
Homo sapiens
Gene: ... Disease relevance of MUM1 Expression of MUM1/ IRF4 selectively clusters with primary effusion lymphoma among lymphomatous effusions: implications for disease histogenesis and pathogenesis. High impact... (+), CD138 (+), MUM1/ IRF4 (+)). Analytical, diagnostic and therapeutic context of MUM1 Second, MUM1/ IRF4...
MeSH term: ... , IRF4 and IRF8 together control the termination of pre- B cell receptor signaling and thus promote... were studied in a series of patients with B- lineage acute lymphoblastic leukemia( ALL ), in which... patients; all the B cell lines possessed distinct gene rearrangement patterns demonstrating their clonal...
MeSH term: ... Disease relevance of Normal Distribution Mice deficient in IRF4 showed normal distribution of B and T lymphocyes at 4 to 5 weeks of age but developed progressive generalized lymphadenopathy. Wilson' s disease protein( WNDP) is a copper- transporting ATPase essential for normal distribution of copper in human cells...
Macaca mulatta
Pan troglodytes


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