Your search matched a total of 128 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of JAK1 To determine the role of the Janus tyrosine kinase( JAK )- STAT pathway in NF- kappaB activation by IFN, we examined NF- kappaB activation in JAK1- deficient mutant human fibrosarcoma cells. We suggest that mutations in the JAK1 and Tyk2 genes may be identified as initial molecular... / Synonyms: JAK-1; JAK1A; JAK1B
Mus musculus
Gene: ... . Although JAK2 was capable of associating with all three of the chimeras, JAK1 co- precipitated only...Disease relevance of Jak1 However, Jak1- deficient, v- abl- transformed cell lines were more.... The nonreceptor tyrosine kinases Jak1 and Jak3, which bind to the v- Abl oncoprotein, are constitutively activated... / Synonyms: JAK-1; Tyrosine-protein kinase JAK1
Rattus norvegicus
Gene: ... Disease relevance of Jak1 This study showed basal cerebral activity of JAK/ STAT signaling pathway, involving Jak1 and Stat3 proteins, and selective activation following ischemia. In the present study, we examined the cellular distribution of Jak1 and Stat3, and activation of the JAK/ STAT pathway following...
Danio rerio
Gene: ... High impact information on jak1 Jak1 kinase is required for cell migrations and anterior... of cytokines in adult tissues, Jak1 kinase has a role in early vertebrate development. Injection of RNA- encoding dominant- negative Jak1 kinases reduces a specific cell migration, epiboly, and results... / Synonyms: JAK-1; Tyrosine-protein kinase JAK1
Sus scrofa
Gene: ... High impact information on JAK1 Adhesion of megakaryocytes to collagen gel also inhibited phosphorylation of JAK1 and JAK2, while MAP kinase phosphorylation was unaffected. Although IBMX stimulated proplatelet formation, it inhibited phosphorylation of JAK1 and MAP kinase. In addition, although...
Xenopus (Silurana) tropicalis
Gene: Synonyms: jak1a; jak1b
MeSH term: ... binding to gp130, signaling through the JAK1- STAT1/ 3 pathway and functions in a cytokine- dependent cell...
MeSH term: ... , degradation of peptides derived from mouse cytomegalovirus pp89 and JAK1 kinase in the presence of PA28 leads...
Homo sapiens
Gene: ... interactions of IL2 Neither Jak1 nor Jak3 was phosphorylated after IL- 2 stimulation of an Epstein- Barr virus.... Cholangiocytes were also shown to express JAK1 and 3 which was phosphorylated following control stimulation... and activation of the Janus kinases Jak1 and Jak3. Furthermore, when both lymphokines were added together...
Homo sapiens
Gene: ... gene expression and apoptosis in either JAK1- deficient HeLa cells( E2A4) or STAT1- deficient cells( U3... recombinant KSHV- encoded vIL- 6 led to rapid induction of JAK1 phosphorylation and a nuclear DNA- binding... interactions of STAT1 Jak1 may therefore be the enzyme that phosphorylates Tyr 701 in Stat91. Both STAT1...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
