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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 54 documents. Results 1 - 10.

Danio rerio
Gene: ... High impact information on lmo2 Co- injection of lmo2 mRNA with scl/ tal1 dramatically extends its... and lmo2, was unaffected, suggesting that hematopoietic cells were present but unable to further differentiate. Biological context of lmo2 Using gene expression analysis and visualization of vessel formation... / Synonyms: LMO-2
Homo sapiens
Gene: ... targeted. The position of the LMO2 breakpoints in T- ALL in the light of the occurrence of TCRD- LMO2... LMO2 activation levels and the consequent pressure for T- ALL development. High impact information... and disease processes. Chemical compound and disease context of LMO2 Combination of all- trans retinoic acid... / Synonyms: LMO-2
Mus musculus
Gene: ... Disease relevance of Lmo2 The LIM- finger protein Lmo2, which is activated in T cell leukemias by chromosomal translocations, is required for yolk sac erythropoiesis. The functional significance of this Lmo2 expression was assessed in teratocarcinomas induced in nude mice by subcutaneous implantation of Lmo2- lac... / Synonyms: LMO-2
Gallus gallus
Gene: ... High impact information on LMO2( 5) Lmo2 is up- regulated in blood island angioblasts thus appearing as one of the earliest markers for endothelial cell commitment....
Rattus norvegicus
Gene: ... Disease relevance of Lmo2 The developmental expression pattern of SRF overlaps significantly with that of myotonic dystrophy protein kinase, a potential upstream regulator, and of the LIM- only genes Lmo1, Lmo2 and Lmo3, whose products belong to a family of proteins known to be strong positive regulators of SRF...
Xenopus laevis
Gene: Synonyms: LMO-2; lmo2-A
MeSH term: ... , and express the zebrafish orthologues of the human T- ALL oncogenes tal1/ scl and lmo2, thus providing... gene on 9p24 in human leukemias. LMO2 is essential for hemopoiesis and angiogenesis, and inappropriate... by DNA blot analyses. Of all common integration sites, a small region of 19 kb in the Hoxa gene locus...
MeSH term: ... with impaired STAT5 activation. In murine erythroleukemia cells, the endogenous Lbd1 and LMO2 proteins exist in a stable complex, whose binding affinity appears greater than that between LMO2 and the bHLH transcription..., hexamethylbisacetamide and butyric acid, all potent inducers of gene expression in Friend erythroleukemia cells...
Xenopus (Silurana) tropicalis
Gene: Synonyms: LMO-2
MeSH term: ... of an oligomeric complex involving Lmo2 which can bind to a bipartite DNA motif comprising two E- box sequences... erythroid cells. Interestingly, Lcrf1 null ES cells injected into wild- type blastocysts contributed to all...


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