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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 89 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Pax5 The transcription factor Pax5 activated endogenous mb- 1 transcription... in chromosomal translocations causing malignancies in humans, and Pax5 expression is deregulated in medulloblastomas. We showed that Pax5 (-/-) Lat (-/-) pro- B cell lines can be infected with recombinant... / Synonyms: Paired box protein Pax-5; Pax-5
Homo sapiens
Gene: ... - PCR studies in t( 8; 21 )- AML showed a similar up- regulation of PAX5 transcript in all of the 8... to negatively control cell growth. CEBPA, PAX5 and PU1 were negative for all cell lines tested except...Disease relevance of PAX5 Deregulated expression of PAX5 in medulloblastoma. Hereby, we analyzed... / Synonyms: ALL3
Danio rerio
Gene: ... High impact information on pax5 Anterior markers pax5 and nkx5. 1 are expressed in expanded domains that include the entire otic epithelium juxtaposed to the hindbrain, and the posterior marker zp23 is not expressed. Otic expression of pax5 requires pax2a and fgf3, mutations in which cause vestibular defects...
Oncorhynchus mykiss
Takifugu rubripes
MeSH term: ... cells. Pax5 restricts the developmental options of lymphoid progenitors to the B cell lineage... alpha 2- 6 sialyltransferase. Independent regulation of the two Pax5 alleles during B- cell development...
MeSH term: ... contains a population of cells of Pax5 -/- origin with the same phenotype as the donor pro- B cells... by PCR analyses, the pre- BI cells in Pax5- deficient bone marrow have undergone D( H )- to- J( H...
MeSH term: ... development of the midbrain and the midbrain- hindbrain boundary at the expense of the forebrain. Pax5 has... role for Pax5 in early B lymphopoiesis and midbrain patterning. Morphogenesis of the posterior midbrain...
MeSH term: ... , PAX5 expression was restricted to the reticulin- producing proliferating tumor areas containing undifferentiated cells; PAX5 was not expressed in the reticulin- free nonproliferating islands undergoing neuronal... of PAX5 correlates positively with cell proliferation and inversely with neuronal differentiation...
MeSH term: ... grafted onto host diencephalons of all three genotypes, and graft axon growth into the optic tract region was assessed. Anatomical context of Diencephalon En, Fgf8, Pax2 and Pax5, exist in a positive feedback loop...


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