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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 44 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of PIAS1 PIAS1 induced apoptosis in both human 293T cells and human osteosarcoma... greater increase in luciferase activity with PIAS1 over that obtained with an equal amount of control antisense cDNA or mutant PIAS1. Distinct effects of PIAS proteins on androgen- mediated gene activation... / Synonyms: E3 SUMO-protein ligase PIAS1
Mus musculus
Gene: ... Disease relevance of Pias1 Since 1985 several carcinogenicity studies have been published about... the former term inert dusts). Psychiatry related information on Pias1 Gabapentin did not affect response... on Pias1 Furthermore GBP expressed from an episome in avirulent parasites, which are unable to synthesise... / Synonyms: E3 SUMO-protein ligase PIAS1
MeSH term: ... modifications and through transacting proteins such as protein inhibitor of activated STAT1( PIAS1)..... Sequence analysis of GALNT3 identified biallelic deleterious mutations in all individuals with FTC...
Xenopus laevis
Gene: Synonyms: pias1-A; xPIAS1
Homo sapiens
Gene: ... of target genes in response to progesterone and other signals. Furthermore, we show that silencing of PIAS1... factor in vitro. We demonstrate that PIAS1 interacts with the PR and serves as its E3 SUMO ligase upon... in risk of nearly all ER/ PR subtypes, although the associations were generally of borderline statistical...
Homo sapiens
Gene: ... loss in patients with liver cirrhosis. Using a murine mammary tumor virus promoter, PIAS1 action was independent of sumoylation whereas with glucocorticoid response element promoter, PIAS1 corepressive action... of sumoylation on hMR properties. Transient transfections demonstrated that PIAS1 is a corepressor of aldosterone...
Homo sapiens
Gene: ... versatile protein kinase. PPM1D also dephosphorylates p53 at phospho- Ser 15. PIAS1 catalyzed... in all esophageal cancers, whereas MDM2 T309G G/ G was associated with a 7- fold increased risk of death... ") are observed in families with germline TP53 mutations: All families had at least one family member...
Homo sapiens
Gene: ... , Interleukin 27 receptor, alpha subunit, PIAS1, BRCA1, Epidermal growth factor receptor, PTK2, Mammalian target... STAT. Inhibition of Stat1- mediated gene activation by PIAS1. Analytical, diagnostic and therapeutic.... The induction and activation of STAT1 by all- trans- retinoic acid are mediated by RAR beta signaling pathways...
MeSH term: ... , PIAS1 action was independent of sumoylation whereas with glucocorticoid response element promoter, PIAS1 corepressive action depended on hMR sumoylation status. Analytical, diagnostic and therapeutic...MTV )- positive cells were observed by immunofluorescence, which suggested that not all the Thy 1. 2- positive...
MeSH term: ... showed that Ubc9 and PIAS1 are markedly expressed in rat adrenal glomerulosa cells. IL- 1 and TNF- alpha... proteins have suggested that one enzyme found in all zones of the adrenal cortex has both 11- and 18...

 

 
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