Gene Review:
PIAS1 - protein inhibitor of activated STAT, 1
Homo sapiens
Synonyms:
DDXBP1, DEAD/H box-binding protein 1, E3 SUMO-protein ligase PIAS1, GBP, GU/RH-II, ...
- Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation. Liu, B., Shuai, K. J. Biol. Chem. (2001)
- Protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1) is a nuclear receptor coregulator expressed in human testis. Tan, J., Hall, S.H., Hamil, K.G., Grossman, G., Petrusz, P., Liao, J., Shuai, K., French, F.S. Mol. Endocrinol. (2000)
- Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells. Gross, M., Liu, B., Tan , J., French, F.S., Carey, M., Shuai, K. Oncogene (2001)
- Protein inhibitor of activated signal transducer and activator of transcription 1 interacts with the N-terminal domain of mineralocorticoid receptor and represses its transcriptional activity: implication of small ubiquitin-related modifier 1 modification. Tallec, L.P., Kirsh, O., Lecomte, M.C., Viengchareun, S., Zennaro, M.C., Dejean, A., Lombès, M. Mol. Endocrinol. (2003)
- The manifold actions of the protein inhibitor of activated STAT proteins on the transcriptional activity of mineralocorticoid and glucocorticoid receptors in neural cells. Tirard, M., Jasbinsek, J., Almeida, O.F., Michaelidis, T.M. J. Mol. Endocrinol. (2004)
- Anticonvulsants in bipolar disorder. Singh, V., Muzina, D.J., Calabrese, J.R. Psychiatr. Clin. North Am. (2005)
- Patterns of illicit drug use of prisoners in police custody in London, UK. Payne-James, J.J., Wall, I.J., Bailey, C. Journal of clinical forensic medicine. (2005)
- Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription. Mowen, K.A., Tang, J., Zhu, W., Schurter, B.T., Shuai, K., Herschman, H.R., David, M. Cell (2001)
- A novel calcium binding site in the galactose-binding protein of bacterial transport and chemotaxis. Vyas, N.K., Vyas, M.N., Quiocho, F.A. Nature (1987)
- PIAS proteins and transcriptional regulation--more than just SUMO E3 ligases? Sharrocks, A.D. Genes Dev. (2006)
- PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein. Lee, H., Quinn, J.C., Prasanth, K.V., Swiss, V.A., Economides, K.D., Camacho, M.M., Spector, D.L., Abate-Shen, C. Genes Dev. (2006)
- Purification and antigenicity of a novel glucan-binding protein of Streptococcus mutans. Smith, D.J., Akita, H., King, W.F., Taubman, M.A. Infect. Immun. (1994)
- Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. Williams, A.J., Bautista, C.C., Chen, R.W., Dave, J.R., Lu, X.C., Tortella, F.C., Hartings, J.A. J. Pharmacol. Exp. Ther. (2006)
- A novel reagentless sensing system for measuring glucose based on the galactose/glucose-binding protein. Salins, L.L., Ware, R.A., Ensor, C.M., Daunert, S. Anal. Biochem. (2001)
- PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Liu, B., Mink, S., Wong, K.A., Stein, N., Getman, C., Dempsey, P.W., Wu, H., Shuai, K. Nat. Immunol. (2004)
- Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Kahyo, T., Nishida, T., Yasuda, H. Mol. Cell (2001)
- Inhibition of Stat1-mediated gene activation by PIAS1. Liu, B., Liao, J., Rao, X., Kushner, S.A., Chung, C.D., Chang, D.D., Shuai, K. Proc. Natl. Acad. Sci. U.S.A. (1998)
- PIAS proteins promote SUMO-1 conjugation to STAT1. Ungureanu, D., Vanhatupa, S., Kotaja, N., Yang, J., Aittomaki, S., Jänne, O.A., Palvimo, J.J., Silvennoinen, O. Blood (2003)
- Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators. Tan, J.A., Hall, S.H., Hamil, K.G., Grossman, G., Petrusz, P., French, F.S. J. Biol. Chem. (2002)
- Activation of p53 by protein inhibitor of activated Stat1 (PIAS1). Megidish, T., Xu, J.H., Xu, C.W. J. Biol. Chem. (2002)
- Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9. Hattori, T., Eberspaecher, H., Lu, J., Zhang, R., Nishida, T., Kahyo, T., Yasuda, H., de Crombrugghe, B. J. Biol. Chem. (2006)
- PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation. Kadaré, G., Toutant, M., Formstecher, E., Corvol, J.C., Carnaud, M., Boutterin, M.C., Girault, J.A. J. Biol. Chem. (2003)
- Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription. Kurihara, I., Shibata, H., Kobayashi, S., Suda, N., Ikeda, Y., Yokota, K., Murai, A., Saito, I., Rainey, W.E., Saruta, T. J. Biol. Chem. (2005)
- Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Jones, M.C., Fusi, L., Higham, J.H., Abdel-Hafiz, H., Horwitz, K.B., Lam, E.W., Brosens, J.J. Proc. Natl. Acad. Sci. U.S.A. (2006)
- ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation. Kotaja, N., Aittomäki, S., Silvennoinen, O., Palvimo, J.J., Jänne, O.A. Mol. Endocrinol. (2000)
- ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation. Zheng, G., Yang, Y.C. J. Biol. Chem. (2004)
- NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers. Okubo, S., Hara, F., Tsuchida, Y., Shimotakahara, S., Suzuki, S., Hatanaka, H., Yokoyama, S., Tanaka, H., Yasuda, H., Shindo, H. J. Biol. Chem. (2004)
- Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction. Liao, J., Fu, Y., Shuai, K. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1. Liang, M., Melchior, F., Feng, X.H., Lin, X. J. Biol. Chem. (2004)
- Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein. Decker, T., Lew, D.J., Cheng, Y.S., Levy, D.E., Darnell, J.E. EMBO J. (1989)
- A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation. Depaux, A., Regnier-Ricard, F., Germani, A., Varin-Blank, N. Oncogene (2007)
- Correlation between pretreatment levels of interferon response genes and clinical responses to an immune response modifier (Imiquimod) in genital warts. Arany, I., Tyring, S.K., Brysk, M.M., Stanley, M.A., Tomai, M.A., Miller, R.L., Smith, M.H., McDermott, D.J., Slade, H.B. Antimicrob. Agents Chemother. (2000)
- Interaction of Protein Inhibitor of Activated STAT (PIAS) Proteins with the TATA-binding Protein, TBP. Prigge, J.R., Schmidt, E.E. J. Biol. Chem. (2006)
- Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity. Liu, B., Yang, Y., Chernishof, V., Loo, R.R., Jang, H., Tahk, S., Yang, R., Mink, S., Shultz, D., Bellone, C.J., Loo, J.A., Shuai, K. Cell (2007)
- Gastrointestinal hormone responses to meals before and after gastric bypass and vertical banded gastroplasty. Kellum, J.M., Kuemmerle, J.F., O'Dorisio, T.M., Rayford, P., Martin, D., Engle, K., Wolf, L., Sugerman, H.J. Ann. Surg. (1990)
- Remedial surgery following failed gastroplasty for morbid obesity. Eckhauser, F.E., Knol, J.A., Strodel, W.E. Ann. Surg. (1983)
- Risks and benefits of gastric bypass in morbidly obese patients with severe venous stasis disease. Sugerman, H.J., Sugerman, E.L., Wolfe, L., Kellum, J.M., Schweitzer, M.A., DeMaria, E.J. Ann. Surg. (2001)