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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 114 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Pitx2 We show that these sites specifically bind to Pitx2 protein in vitro and that in transfected neuroblastoma cells, the Pitx2 binding sites contribute to the basal activity of the Gad1 promoter. Further, dysgenesis of the Pitx2 (-)(/)(-) extraocular muscle and thickening of the mesothelial layer... / Synonyms: Homeobox protein PITX2; Pitx2a; Pitx2b
Homo sapiens
Gene: ... Disease relevance of PITX2 Mutation in PITX2 is associated with ring dermoid of the cornea. In the developmental glaucomas, mutations in the PITX2 gene on chromosome 4q25 have been associated with Rieger... could be relevant to the pathophysiology of hypertension in humans. Mutations in PITX2 may contribute... / Synonyms: Homeobox protein PITX2; ALL1-responsive protein ARP1
Danio rerio
Gene: ... High impact information on pitx2a Asymmetric isoform expression occurs in non- overlapping domains, with pitx2c in left dorsal diencephalon and developing gut and pitx2a in left heart primordium. Ectopic expression of pitx2 isoforms results in distinct morphological and molecular phenotypes, indicating that pitx... / Synonyms: Homeobox protein PITX2; pitx2a; pitx2b
Rattus norvegicus
Gene: ... High impact information on Pitx2 Three different transcripts of the homeodomain gene termed pituitary homeobox( Ptx) 2( Pitx2/ Brx/ Rieg/ Solurshin/ Arp) were cloned from different species encoding.... Analytical, diagnostic and therapeutic context of Pitx2 The expression pattern of rPtx2 was further... / Synonyms: Homeobox protein PITX2; Pitx-2; Pitx2c
Xenopus (Silurana) tropicalis
Gene: ... High impact information on pitx2 The experimental manipulation of early embryologic events, resulting in the misexpression of the homeobox transcription factor pitx2, is associated with subsequent..., or polyethyleneimine- based gene transfer of Xnr- 1 mRNA in the right LPM induces Xnr- 1 and pitx2 in the same side... / Synonyms: pitx2-A; pitx2c
Gallus gallus
Gene: ... High impact information on PITX2 The transcription factor Pitx2 mediates situs- specific... genes Pitx2 and Nkx3. We further constructed RCAS retroviral vectors expressing dominant negative Pitx2...2 isoforms( Pitx2a and Pitx2c) that differ in the region 5' to the homeodomain, in early chick...
Xenopus laevis
Gene: ... High impact information on Pitx2 We report here that similar to effects of ectopic TGF betas, right... as well as altered Pitx2 expression in the lateral plate mesoderm. Injection of the antisense morpholino... expression of Xnr- 1 and Pitx2, and caused the organ reversal in the injected embryos. Time course analysis...
MeSH term: ... EPHB2 suppresses clonogenic growth. CITED2 and TFAP2 were detected at the Pitx2c promoter in embryonic hearts, and they activate Pitx2c transcription in transient transfection assays. IFN- gamma induced...
Xenopus laevis
Gene: Synonyms: pitx2c
MeSH term: ... of the retina, optic nerve and in the sclera. As Pitx2 is not expressed in the optic stalk, an essential function of PITX2 protein in neural crest is to regulate an extrinsic factor( s) required for development...

 

 
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