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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 62 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Prox1 Mouse Prox1 gene mapped to position 106. 3 cM from the centromere... promoted by Prox1 haploinsufficiency cause adult- onset obesity. Prox1 heterozygous mice are a new model for adult- onset obesity and lymphatic vascular disease. Expression of Prox1 was reduced in pancreatic... / Synonyms: Homeobox prospero-like protein PROX1; PROX-1
Homo sapiens
Gene: ... Disease relevance of PROX1 Mutations and aberrant DNA methylation of the PROX1 gene in hematologic...% of the main lymphatic lineage- specific genes, including PROX1, a master regulator of lymphatic development... in PROX1 dependent misregulation of differentiation and proliferation processes in bilary tract carcinomas... / Synonyms: Homeobox prospero-like protein PROX1; PROX-1
Danio rerio
Gene: ... High impact information on prox1 In u- boot mutant embryos, slow muscle precursors abort their developmental program, failing to activate expression of the homeobox gene prox1 and transfating into muscle cells with fast fiber properties. In situ hybridization demonstrates that prox1 colocalizes with ff1a... / Synonyms: prox1
Xenopus laevis
Gene: ... Disease relevance of PROX1 Morpholino- mediated knockdown of the lymphangiogenic factor Prox1 caused lymph vessel defects and lymphedema by impairing lymphatic commitment....
Gallus gallus
Gene: ... High impact information on PROX1 In transfection assays, Mafs and Prox1 activated the chicken beta... of transcription factors associated with the development of horizontal or bipolar neurons, such as Prox1, Chx10...A, GABA, Prox1, AP2alpha, Pax6, islet1, and Lim1+ 2. Prox1 is a specific marker of the lymphatic...
MeSH term: ... that Prox1 is required for hepatocyte migration. Selective repopulation of normal mouse liver by Fas/ CD95...
Homo sapiens
Gene
MeSH term: ... , hypertension, and cardiovascular diseases. Lymphatic vascular defects promoted by Prox1 haploinsufficiency...
MeSH term: ... Disease relevance of Vascular Diseases The presence of cystathionine beta- synthase deficiency was confirmed in 18 of 23 patients with vascular disease who had hyperhomocysteinemia. These findings suggest a new drug target to treat homocystinuria and homocysteine- related vascular disease. Prox1 heterozygous...
MeSH term: ... that the homeobox gene Prox1 is expressed in a subpopulation of endothelial cells that by budding and sprouting give...

 

 
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