Gene Review:
Prox1 - prospero homeobox 1
Mus musculus
Synonyms:
A230003G05Rik, Homeobox prospero-like protein PROX1, PROX-1, Prospero homeobox protein 1
- Characterization of the mouse Prox1 gene. Tomarev, S.I., Zinovieva, R.D., Chang, B., Hawes, N.L. Biochem. Biophys. Res. Commun. (1998)
- Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Harvey, N.L., Srinivasan, R.S., Dillard, M.E., Johnson, N.C., Witte, M.H., Boyd, K., Sleeman, M.W., Oliver, G. Nat. Genet. (2005)
- Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells. Takahashi, M., Yoshimoto, T., Shimoda, M., Kono, T., Koizumi, M., Yazumi, S., Shimada, Y., Doi, R., Chiba, T., Kubo, H. Neoplasia (2006)
- Pax-6, Prox 1, and Chx10 homeobox gene expression correlates with phenotypic fate of retinal precursor cells. Belecky-Adams, T., Tomarev, S., Li, H.S., Ploder, L., McInnes, R.R., Sundin, O., Adler, R. Invest. Ophthalmol. Vis. Sci. (1997)
- Hepatocyte migration during liver development requires Prox1. Sosa-Pineda, B., Wigle, J.T., Oliver, G. Nat. Genet. (2000)
- Prox1 function is required for the development of the murine lymphatic system. Wigle, J.T., Oliver, G. Cell (1999)
- Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. Maruyama, K., Ii, M., Cursiefen, C., Jackson, D.G., Keino, H., Tomita, M., Van Rooijen, N., Takenaka, H., D'Amore, P.A., Stein-Streilein, J., Losordo, D.W., Streilein, J.W. J. Clin. Invest. (2005)
- Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells. Wang, J., Kilic, G., Aydin, M., Burke, Z., Oliver, G., Sosa-Pineda, B. Dev. Biol. (2005)
- Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor. B??ckhed, F., Crawford, P.A., O'donnell, D., Gordon, J.I. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring. Bick-Sander, A., Steiner, B., Wolf, S.A., Babu, H., Kempermann, G. Proc. Natl. Acad. Sci. U.S.A. (2006)
- T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. Schacht, V., Ramirez, M.I., Hong, Y.K., Hirakawa, S., Feng, D., Harvey, N., Williams, M., Dvorak, A.M., Dvorak, H.F., Oliver, G., Detmar, M. EMBO J. (2003)
- Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Burke, Z., Oliver, G. Mech. Dev. (2002)
- Co-expression pattern of Shh with Prox1 and that of Nkx2.2 with Mash1 in mouse taste bud. Miura, H., Kusakabe, Y., Kato, H., Miura-Ohnuma, J., Tagami, M., Ninomiya, Y., Hino, A. Gene Expr. Patterns (2003)
- Isolation and Characterization of A Novel Mouse Lymphatic Endothelial Cell Line: SV-LEC. Ando, T., Jordan, P., Joh, T., Wang, Y., Jennings, M.H., Houghton, J., Alexander, J.S. Lymphatic research and biology. (2005)
- Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Brandt, M.D., Jessberger, S., Steiner, B., Kronenberg, G., Reuter, K., Bick-Sander, A., von der Behrens, W., Kempermann, G. Mol. Cell. Neurosci. (2003)
- Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli. Kronenberg, G., Reuter, K., Steiner, B., Brandt, M.D., Jessberger, S., Yamaguchi, M., Kempermann, G. J. Comp. Neurol. (2003)
- Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mishima, K., Watabe, T., Saito, A., Yoshimatsu, Y., Imaizumi, N., Masui, S., Hirashima, M., Morisada, T., Oike, Y., Araie, M., Niwa, H., Kubo, H., Suda, T., Miyazono, K. Mol. Biol. Cell (2007)
- Regulation of proliferation, cell fate specification and differentiation by the homeodomain proteins Prox1, Six3, and Chx10 in the developing retina. Dyer, M.A. Cell Cycle (2003)
- Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation. Govindarajan, V., Overbeek, P.A. Development (2001)