Your search matched a total of 499 documents. Results 1 - 10.
Homo sapiens
Gene: ... show that all cytokines that utilize gp130 sequentially induce two distinct forms of STAT3 in all...Disease relevance of STAT3 The suppressive activity of the culture supernatants from the melanoma..., comparable to the effects observed with STAT3 RNAi transduction. Increased IL- 6Ralpha expression...
Mus musculus
Gene: ... Disease relevance of Stat3 However, estrogen- induced decrease in body weight was dependent on Stat3 activation in the brain. In this study, we analyzed the mechanism by which a Stat3 deficiency... of targeting Stat3 in in vivo growth of C4HD breast tumors. In the present study, we explored the capacity...
Bos taurus
Gene: ... Disease relevance of STAT3 To define the molecular mechanisms involved, the effect of peroxynitrite... and tumor angiogenesis- signal transducer and activator of transcription 3( STAT3) and hypoxia- inducible factor- 1( HIF- 1). CONCLUSIONS: The present study showed that STAT3 is expressed and activated...
Danio rerio
Gene: ... High impact information on stat3 2. The stat5. 1 gene shows a high level of conservation with the single stat5 gene found in other teleosts and lies next to the stat3 gene, in the same relative... and vertebrate STATs 3 and 5, we isolated, sequenced, and analyzed the zebrafish Stat3( z- Stat3) gene and a 500... / Synonyms: z-Stat3
Homo sapiens
Gene: ... : End- stage HCV and ALD cirrhosis is characterized by impaired Stat3 DNA- binding possibly through up... to STAT3 and blocks transcriptional activation. PIAS3 and Smad3 interact with each other at the endogenous... domain of Smad3. Activation of Smad transcriptional activity by protein inhibitor of activated STAT3...
Rattus norvegicus
Gene: ... in rats. Expression of all Stat3 mutants had no effect on NGF- induced neurite outgrowth. In contrast...Disease relevance of Stat3 Unexpectedly, activated Stat5 was also detected in the nuclei of untreated control rats. cDNA clones representing Stat3 and two isoforms of Stat5b were isolated from a c...
Gallus gallus
Gene: ... activation of STAT3 and to a lesser extent STAT1 signal transduction pathways. All- trans- retinoic acid... of two forms of STAT3 in chick ciliary ganglion neurons. High impact information on RCJMB04_ 38l20 Matrix- independent activation of phosphatidylinositol 3- kinase, Stat3, and cyclin A- associated Cdk2 Is essential...
MeSH term: ... transduction pathway through STAT3 in a keratinocyte cell line, demonstrating a direct action of this ligand... observed in a number of glioma, prostate, kidney and breast carcinoma cell lines or tumour specimens. All.... In parallel with IgG- induced elevations in intracellular cyclic AMP levels in the same cell line, all 20...
MeSH term: ... of this protein. Transgenic mice with keratinocytes expressing a constitutively active Stat3( K5. Stat3C mice... lesions in K5. Stat3C mice requires cooperation between Stat3 activation in keratinocytes and activated... skin patches; the paternal mutation( R1226X) remained present in all cell samples. In the patients...
Homo sapiens
Gene: ... ( IL- 6/ gp130/ STAT3) pathway has been reported to play an important role in the pathogenesis...Da protein, corresponding to Stat3, and a 36 kDa protein, most likely a CRE- like site binding protein( s... with this epitope. Recently, we showed that the magnitude of Stat3 binding to three IL- 6 motifs on the human gamma...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
