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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 1611 documents. Results 1 - 10.

Homo sapiens
Gene: ... ") are observed in families with germline TP53 mutations: All families had at least one family member... of treatment in all 26 analyzed tumor samples independently of ATM and TP53 gene status, whereas 6 of 26 B...Somatic disease relevance of TP53 Frequent somatic mutations in PTEN and TP53 are mutually...
MeSH term: ... p53. Sequence analysis of tumor protein 53 gene( TP53) revealed a missense mutation in exon 5... affected, as is the gene( TP53) that codes for the p53 protein. High impact information on Genes, p53...) expression, without apparent stabilisation of the TP53 gene product. However, it is uncertain whether p53... / Synonyms: Gene, TP53; Genes, TP53; TP53 Gene
Homo sapiens
Gene: ... High impact information on TP53TG3 Immunohistochemical analysis using cancer cells( HeLa or H1299) that had been transfected with plasmid DNA designed to express the MYC- fused TP53TG3 proteins indicated... and characterization of a novel TP53- inducible gene, termed TP53TG3( TP53 target gene 3).... / Synonyms: TP53TG3A
Homo sapiens
Gene: ... High impact information on TP53RK A human protein kinase, p53- related protein kinase( PRPK... in the cell cycle and cell apoptosis through phosphorylation of p53. Biological context of TP53RK To identify... sequence tag CGI- 121 by which a 20- kDa protein was encoded. Anatomical context of TP53RK However... / Synonyms: Atypical serine/threonine protein kinase TP53RK; EKC/KEOPS complex subunit TP53RK; TP53-regulating kinase
Homo sapiens
Gene: ... , which lacks wild- type TP53 and expresses no endogenous TP53TG5, revealed a growth- suppressive effect of the TP53TG5 gene product. High impact information on C20orf10 Furthermore, immunohistochemical studies, following transfection of T98G with plasmid designed to express green fluorescent protein- fused TP53TG5... / Synonyms: TP53-inducible gene 5 protein; TP53-target gene 5 protein
Homo sapiens
Gene: ... Disease relevance of TP53AP1 Isolation of a novel TP53 target gene from a colon cancer cell line carrying a highly regulated wild- type TP53 expression system. High impact information on TP53AP1 Both... containing transcripts and are up- regulated by TP53, confirming that HIC- 1 is a TP53 target gene. Here we... / Synonyms: TP53-inducible gene 1 protein; TP53-target gene 1 protein; TP53AP1
Homo sapiens
Gene: ... Disease relevance of TP53INP1 CONCLUSION: TP53INP1- positive rate decreases with the progression of gastric cancer. TP53INP1 expression was significantly decreased( 43. 9 %) in poorly differentiated adenocarcinoma compared with well or moderately differentiated adenocarcinoma( 81. 6 %). We report here that TP53... / Synonyms: TP53DINP1; TP53INP1A; TP53INP1B
Homo sapiens
Gene: ... Disease relevance of TP53BP1 We describe the fusion of TP53BP1 to PDGFRB in a patient... conclude that TP53BP1- PDGFRB is a novel imatinib target in atypical chronic myeloid leukemia. 53BP1... diminished in p202- expressing prostate cancer cells. High impact information on TP53BP1 Using a human cell...
Homo sapiens
Gene: ... Disease relevance of TP53BP2 We investigated the association of the TP53BP2 locus with gastric...- amyloid peptide mediated toxicity. Psychiatry related information on TP53BP2 These findings suggest... pathophysiology of Alzheimer' s disease. High impact information on TP53BP2 The core domain contains the sequence...
Rattus norvegicus
Gene: ... Disease relevance of Tp53 Experiments in LNCaP prostate cancer cells reveal that AR inhibits p53... information on Tp53 The present results provide additional support for the view that NF- kappaB activation... requirements for p53 inactivation. High impact information on Tp53 The cells maintain high telomerase activity...

 

 
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