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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 148 documents. Results 1 - 10.

Homo sapiens
Gene: ... intestine and thymus, all of which contain proliferating cells. Two enzymes of base excision repair( BER... all free- living organisms have developed strategies to protect their genome against the presence...Disease relevance of UNG Although this UNG form was fully active and stable when expressed... / Synonyms: UNG1; UNG15; UNG2
Mus musculus
Gene: ... Disease relevance of Ung Mutation frequencies and AID activation state in B- cell lymphomas from Ung- deficient mice. Lymphoid hyperplasia occurs very early in otherwise healthy Ung- deficient mice... in mouse macrophages. High impact information on Ung Uracil- DNA glycosylase( UNG )- deficient mice reveal... / Synonyms: UNG1; UNG2; Ung1
UNG1  -  Ung1p
Saccharomyces cerevisiae S288c
Gene: ... elements have no essential role in the DNA damage response. All phenotypes of the dut1- 1 mutant...High impact information on UNG1 Analyses with isogenic uracil- DNA- glycosylase( UNG1) deficient... of uracil into DNA and the attempted repair of this damage by UNG1- mediated excision repair. Genetic...
Pseudomonas aeruginosa PAO1
Gene: ... Disease relevance of ung In this study, we chose G+ C- rich genome containing bacteria( Pseudomonas aeruginosa and Mycobacterium smegmatis) as model organisms to investigate the biological significance of ung....
Escherichia coli UTI89
Gene: ... Disease relevance of ung Quantitative determination of uracil residues in Escherichia coli DNA: Contribution of ung, dug, and dut genes to uracil avoidance. Characterization of the uracil- DNA glycosylase... on ung The low molecular weight of the replication intermediates is unchanged by blocking linear DNA...
Escherichia coli CFT073
Gene: ... Disease relevance of ung Quantitative determination of uracil residues in Escherichia coli DNA: Contribution of ung, dug, and dut genes to uracil avoidance. Characterization of the uracil- DNA glycosylase... on ung The low molecular weight of the replication intermediates is unchanged by blocking linear DNA...
Gallus gallus
Gene: ... High impact information on UNG In hypermutating chicken DT40 B cells, most IgV mutations are d... to be further processed by uracil DNA glycosylase( UNG ), UNG inactivation should block gene conversion and induce transition mutations. Ig gene conversion is almost completely extinguished in the UNG- deficient...
Rattus norvegicus
Gene: ... Disease relevance of Ung 2. There was an approx three- fold increase in the activity of uracil- DNA... examined. High impact information on Ung[ 14C] Methoxyamine permits one to follow the formation of AP sites... -- 24 h after partial hepatectomy. Biological context of Ung Expression and activity of the DNA repair...
Escherichia coli O157:H7 str. EDL933
Gene: ... Disease relevance of ung Quantitative determination of uracil residues in Escherichia coli DNA: Contribution of ung, dug, and dut genes to uracil avoidance. T5 phage containing 12% uracil can replicate in uracil- DNA glycosylase- deficient( ung) hosts with high efficiency, but fail to replicate in ung+ hosts...
Escherichia coli str. K-12 substr. MG1655
Gene: ... Disease relevance of ung The levels of ung gene expression remain constant up to the early...- DNA glycosylase inhibitor( Ugi) protein inactivates uracil- DNA glycosylase( Ung) by acting as a DNA mimic to bind Ung in an irreversible complex. We have designed a novel coupled transcriptional construct...

 

 
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