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Chemical Compound Review:

Dithioglycol ethane-1,2-dithiol

Synonyms: PubChem12844, ACMC-1AWL1, AG-F-86730, ANW-31945, HSDB 2828, ...

Tjiu, J.W. et al., Xu, S. et al., Bianchi, E. et al., Weber, T.P. et al.

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Disease relevance of Ethylene mercaptan

We report on a 22-year-old female chemistry student who developed widespread erythema multiforme-like lesions after local contact with 1,2-ethanedithiol [1].
1,2-Ethanedithiol-induced erythema multiforme-like contact dermatitis [1].

High impact information on Ethylene mercaptan

Substitution of L-DTT with 1,2-ethanedithiol in ZnCl(2) solutions led to a comparable loss of rho poly(C)-dependent ATPase activity, indicating that other metal chelates can serve as efficient inhibitors [2].
At first, a cleaned gold electrode was immersed in thiol-functionalized poly(St-co-AA) nanosphere latex prepared by emulsifier-free emulsion polymerization of St with AA and function with dithioglycol to assemble the nanospheres, then gold nanoparticles were chemisorbed onto the thiol groups [3].
Among the cleavage procedures evaluated for the removal of the five Mtr groups only TFMSA/TFA/1,2-ethanedithiol (1:89:10 by vol) brought deblocking to completion; a substantial level of impurities originated, however, from these procedures [4].

Analytical, diagnostic and therapeutic context of Ethylene mercaptan

The patient had a positive patch test to 1,2-ethanedithiol, whereas none of 30 healthy subjects showed a positive reaction [1].

References

1,2-Ethanedithiol-induced erythema multiforme-like contact dermatitis. Tjiu, J.W., Chu, C.Y., Sun, C.C. Acta Derm. Venereol. (2004) [Pubmed]
Metal-1,4-dithio-2,3-dihydroxybutane chelates: novel inhibitors of the Rho transcription termination factor. Weber, T.P., Widger, W.R., Kohn, H. Biochemistry (2003) [Pubmed]
A novel method to construct a third-generation biosensor: self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres. Xu, S., Han, X. Biosensors & bioelectronics. (2004) [Pubmed]
Synthetic peptides for Plasmodium vivax malaria sero-epidemiology. Application of Fmoc-polyamide and displacement chromatography. Bianchi, E., del Giudice, G., Verdini, A.S., Pessi, A. Int. J. Pept. Protein Res. (1991) [Pubmed]

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