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Chemical Compound Review

PubChem20208     oxan-2-one

Synonyms: SureCN37722, CHEMBL452383, NSC-6247, ACMC-1B23E, AG-E-82783, ...
 
 
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High impact information on delta-Valeryllactone

  • Thus, the lowest calculated transition state for the conversion of the half-chair, most stable, conformer of delta-valerolactone to the boat-type conformer lies only 1.93 kcal/mol above the former [1].
  • The alkylating potential of beta-propiolactone (BPL), beta-butyrolactone (BBL), gamma-butyrolactone, and delta-valerolactone, which can be formed by the in vivo nitrosation of primary amino acids, was investigated kinetically [2].
  • A formal total synthesis of cephalotaxine (CET), the parent structure of antileukemia Cephalotaxus alkaloids, was achieved through a novel synthesis of the pentacyclic amino enone 4 by a rapid annulation of readily available beta-(3,4-methylenedioxy)phenethylamine (2), delta-valerolactone, and bromoacetone [3].
  • Inactivation stiochiometry determined with 14C-labeled 3-(1-naphthyl)-6(E)-iodomethylene tetrahydropyran-2-one was found to correspond to the active-site number [4].
  • Human aldehyde dehydrogenase (EC 1.2.1.3) isozymes E1 and E2 were irreversibly inactivated by stoichiometric concentrations of the haloenol lactones 3-isopropyl-6(E)-bromomethylene tetrahydro-pyran-2-one and 3-phenyl-6(E)-bromomethylene tetrahydropyran-2-one [4].
 

Associations of delta-Valeryllactone with other chemical compounds

References

  1. Highly diastereoselective hydrogenations leading to beta-hydroxy delta-lactones in hydroxy-protected form. A modified view of delta-lactone conformations. Brandänge, S., Färnbäck, M., Leijonmarck, H., Sundin, A. J. Am. Chem. Soc. (2003) [Pubmed]
  2. A kinetic approach to the alkylating potential of carcinogenic lactones. Manso, J.A., Pérez-Prior, M.T., García-Santos, M.d.e.l. .P., Calle, E., Casado, J. Chem. Res. Toxicol. (2005) [Pubmed]
  3. A novel formal total synthesis of cephalotaxine. Li, W.D., Ma, B.C. J. Org. Chem. (2005) [Pubmed]
  4. Haloenol lactones as inactivators and substrates of aldehyde dehydrogenase. Mukerjee, N., Dryjanski, M., Dai, W., Katzenellenbogen, J.A., Pietruszko, R. J. Protein Chem. (1996) [Pubmed]
  5. An evaluation of a new lactic acid polymer drug delivery system: a preliminary report. Sawada, Y., Ohkubo, T., Kudoh, M., Sugawara, K., Otani, K., Sasaki, J. British journal of plastic surgery. (1994) [Pubmed]
 
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