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Chemical Compound Review

HTHQ     4-hexoxy-2,3,6-trimethyl- phenol

Synonyms: ACMC-1C0E0, CCRIS 7478, AG-D-93525, HTHQ-2,3,5, LS-7429, ...
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High impact information on CCRIS 7478


Analytical, diagnostic and therapeutic context of CCRIS 7478


  1. Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat. Ito, N., Hasegawa, R., Imaida, K., Tamano, S., Hagiwara, A., Hirose, M., Shirai, T. Mutat. Res. (1997) [Pubmed]
  2. Strong inhibition of 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone. Hirose, M., Akagi, K., Hasegawa, R., Satoh, T., Nihro, Y., Miki, T., Sugimura, T., Ito, N. Jpn. J. Cancer Res. (1993) [Pubmed]
  3. 1-O-hexyl-2,3,5-trimethylhydroquinone inhibits IkappaB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function. Liu, W., Itoigawa, M., Miki, T., Nishikawa, H., Sugiyama, S., Ishikawa, N. J. Pharm. Pharmacol. (2002) [Pubmed]
  4. Prevention by antioxidants of heterocyclic amine-induced carcinogenesis in a rat medium-term liver bioassay: results of extended and combination treatment experiments. Hirose, M., Futakuchi, M., Tanaka, H., Orita, S.I., Ito, T., Miki, T., Shirai, T. Eur. J. Cancer Prev. (1998) [Pubmed]
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