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Chemical Compound Review:

Diheptyl ether 1-heptoxyheptane

Synonyms: n-Heptyl Ether, HEPTYL ETHER, ACMC-209nb4, ANW-34478, NSC-97274, ...

Poon, R. et al., Chen, Y. et al.

Poon, Wade, Valli, Chu,

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Disease relevance of Diheptyl ether

Both heptyl ether derivatives (R- and S-isomers) showed similar in vitro photosensitizing efficacy and limited skin phototoxicity and were found to localize in mitochondria [1].
A 4-week oral study was conducted in male rats to characterize and compare the toxicity of four aliphatic ethers (butyl ether, BE; ethyl hexyl ether, EHxE; methyl heptyl ether, MHpE; and 1,6-dimethoxyhexane, DMH) which have been proposed as high-cetane diesel additives [2].

References

Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides. Chen, Y., Sumlin, A., Morgan, J., Gryshuk, A., Oseroff, A., Henderson, B.W., Dougherty, T.J., Pandey, R.K. J. Med. Chem. (2004) [Pubmed]
Short-term oral toxicity of butyl ether, ethyl hexyl ether, methyl heptyl ether and 1,6-dimethoxyhexane in male rats and the role of 2-methoxyacetic acid. Poon, R., Wade, M., Valli, V.E., Chu, I. Toxicology (2005) [Pubmed]

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