Chemical Compound Review:
AC1NRATB (2S)-2-amino-3- (dimethylcarbamoyl)propanoi...
Synonyms:
N4,N4-DIMETHYL-ASPARAGINE
- Suppression of dimethylhydrazine-induced carcinogenesis in mice by dietary addition of the Bowman-Birk protease inhibitor. St Clair, W.H., Billings, P.C., Carew, J.A., Keller-McGandy, C., Newberne, P., Kennedy, A.R. Cancer Res. (1990)
- Activation of the colon carcinogen 1,2-dimethylhydrazine in a rat colon cell-mediated mutagenesis assay. Oravec, C.T., Jones, C.A., Huberman, E. Cancer Res. (1986)
- A thermostable antigen characteristic for carcinogen-induced rat intestinal tumors. Abeyounis, C.J., Milgrom, F. J. Immunol. (1976)
- Glomerular abnormalities in long-term experimental diabetes. Role of hemodynamic and nonhemodynamic factors and effects of antihypertensive therapy. Fujihara, C.K., Padilha, R.M., Zatz, R. Diabetes (1992)
- Disinhibition of maternal behavior following neurotoxic lesions of the hypothalamus in primigravid rats. Mann, P.E., Babb, J.A. Brain Res. (2004)
- Hypothalamic administration of cAMP agonist/PKA activator inhibits both schedule feeding and NPY-induced feeding in rats. Sheriff, S., Chance, W.T., Iqbal, S., Rizvi, T.A., Xiao, C., Kasckow, J.W., Balasubramaniam, A. Peptides (2003)
- A comparison of suicide and undetermined deaths in psychiatric patients. Nuttall, E.A., Evenson, R.C., Cho, D.W. Suicide & life-threatening behavior. (1980)
- Organization of inputs to the dorsomedial nucleus of the hypothalamus: a reexamination with Fluorogold and PHAL in the rat. Thompson, R.H., Swanson, L.W. Brain Res. Brain Res. Rev. (1998)
- Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat. Wang, Q., Bing, C., Al-Barazanji, K., Mossakowaska, D.E., Wang, X.M., McBay, D.L., Neville, W.A., Taddayon, M., Pickavance, L., Dryden, S., Thomas, M.E., McHale, M.T., Gloyer, I.S., Wilson, S., Buckingham, R., Arch, J.R., Trayhurn, P., Williams, G. Diabetes (1997)
- Effect of selenium on the induction of breast fibroadenomas by adenovirus type 9 and 1,2-dimethylhydrazine-induced bowel carcinogenesis in rats. Ankerst, J., Sjögren, H.O. Int. J. Cancer (1982)
- Influence of dietary cis and trans fats on DMH-induced colon tumors, steroid excretion, and eicosanoid production in rats prone to colon cancer. Sugano, M., Watanabe, M., Yoshida, K., Tomioka, M., Miyamoto, M., Kritchevsky, D. Nutrition and cancer. (1989)
- Prevention of development of N,N'-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice. Lu, H., Kyo, E., Uesaka, T., Katoh, O., Watanabe, H. Int. J. Mol. Med. (2002)
- Rat colonic lipid peroxidation and antioxidant status: the effects of dietary luteolin on 1,2-dimethylhydrazine challenge. Manju, V., Balasubramaniyan, V., Nalini, N. Cell. Mol. Biol. Lett. (2005)
- Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation. Brown, W.A., Skinner, S.A., Malcontenti-Wilson, C., Vogiagis, D., O'Brien, P.E. Gut (2001)
- The influence of surgical transection and anastomosis on the rate of cell proliferation in the colonic epithelium of normal and DMH-treated rats. Barkla, D.H., Tutton, P.M. Carcinogenesis (1983)
- Cardiovascular regulation through hypothalamic GABA(A) receptors in a genetic absence epilepsy model in rat. Aker, R.G., Onat, F.Y. Epilepsia (2002)
- Nicotine up-regulates expression of orexin and its receptors in rat brain. Kane, J.K., Parker, S.L., Matta, S.G., Fu, Y., Sharp, B.M., Li, M.D. Endocrinology (2000)
- Chemical characterization of leptin-activated neurons in the rat brain. Elias, C.F., Kelly, J.F., Lee, C.E., Ahima, R.S., Drucker, D.J., Saper, C.B., Elmquist, J.K. J. Comp. Neurol. (2000)
- Leukotrienes are involved in leukocyte recruitment induced by live Histoplasma capsulatum or by the beta-glucan present in their cell wall. Medeiros, A.I., Silva, C.L., Malheiro, A., Maffei, C.M., Faccioli, L.H. Br. J. Pharmacol. (1999)
- Predominant mutation of codon 41 of the beta-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol. Koesters, R., Hans, M.A., Benner, A., Prosst, R., Boehm, J., Gahlen, J., Doeberitz, M.K. Carcinogenesis (2001)
- Glutamate receptors in the raphe pallidus mediate brown adipose tissue thermogenesis evoked by activation of dorsomedial hypothalamic neurons. Cao, W.H., Morrison, S.F. Neuropharmacology (2006)
- Inhibition of development of N,N'-dimethylhydrazine-induced rat colonic aberrant crypt foci by pre, post and simultaneous treatments with 24R,25-dihydroxyvitamin D3. Salim, E.I., Wanibuchi, H., Taniyama, T., Yano, Y., Morimura, K., Yamamoto, S., Otani, S., Nishizawa, Y., Morii, H., Fukushima, S. Jpn. J. Cancer Res. (1997)
- Evidence of altered hypothalamic pro-opiomelanocortin/ neuropeptide Y mRNA expression in tubby mice. Guan, X.M., Yu, H., Van der Ploeg, L.H. Brain Res. Mol. Brain Res. (1998)
- Chemopreventive potential of luteolin during colon carcinogenesis induced by 1,2-dimethylhydrazine. Manju, V., Nalini, N. Ital. J. Biochem. (2005)
- Induction of neuropeptide Y expression in dorsomedial hypothalamus of diet-induced obese mice. Guan, X.M., Yu, H., Trumbauer, M., Frazier, E., Van der Ploeg, L.H., Chen, H. Neuroreport (1998)
- Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. Devasena, T., Rajasekaran, K.N., Menon, V.P. Pharmacol. Res. (2002)
- Comparison of 7-medG formation in white blood cells, liver and target organs in rats treated with methylating carcinogens. Bianchini, F., Wild, C.P. Carcinogenesis (1994)
- The role of amygdala and hypothalamus in GABAA antagonist bicuculline-induced cardiovascular responses in conscious rats. Gören, Z., Aslan, N., Berkman, K., Oktay, S., Onat, F. Brain Res. (1996)
- An assessment of the risk of neoplasia in long-term ileal reservoirs using the DMH rodent model. Heppell, J., De Zubiria, M., Brais, M.F., Durh, M.A., Carioto, S., Boivin, Y., Potvin, C. Dis. Colon Rectum (1990)
- Changes in cell proliferation and morphology in the large intestine of normal and DMH-treated rats following colostomy. Barkla, D.H., Tutton, P.J. Dis. Colon Rectum (1987)