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Chemical Compound Review

AG-A-29102     1-oxido-2-pyridin-2-yl-indol- 3-one

Synonyms: AC1Q1WBT, CTK5I4433, ZINC02573143, AR-1C7000, AKOS004904829, ...
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High impact information on 1-oxido-2-pyridin-2-yl-indol-3-one


Analytical, diagnostic and therapeutic context of 1-oxido-2-pyridin-2-yl-indol-3-one


  1. 2,2'-Pyridylisatogen tosylate antagonizes P2Y1 receptor signaling without affecting nucleotide binding. Gao, Z.G., Mamedova, L., Tchilibon, S., Gross, A.S., Jacobson, K.A. Biochem. Pharmacol. (2004) [Pubmed]
  2. Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: potentiation by 2,2'-pyridylisatogen tosylate. Ren, L.M., Burnstock, G. Br. J. Pharmacol. (1997) [Pubmed]
  3. Potentiation by 2,2'-pyridylisatogen tosylate of ATP-responses at a recombinant P2Y1 purinoceptor. King, B.F., Dacquet, C., Ziganshin, A.U., Weetman, D.F., Burnstock, G., Vanhoutte, P.M., Spedding, M. Br. J. Pharmacol. (1996) [Pubmed]
  4. Prior glucose deprivation increases the first phase of glucose-induced insulin response: possible involvement of endogenous ATP and (or) ADP. Chapal, J., Bertrand, G., Hillaire-Buys, D., Gross, R., Loubatières-Mariani, M.M. Can. J. Physiol. Pharmacol. (1993) [Pubmed]
  5. Role of spin trapping and P2Y receptor antagonism in the neuroprotective effects of 2,2'-pyridylisatogen tosylate and related compounds. Menton, K., Spedding, M., Gressens, P., Villa, P., Williamson, T., Markham, A. Eur. J. Pharmacol. (2002) [Pubmed]
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