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Chemical Compound Review

CCRIS 470     4-(nitrosomethylamino)butan- 2-one

Synonyms: M-3-OB, AC1Q5CIP, LS-46830, AR-1F9419, AC1L2UR5, ...
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Disease relevance of M-3-OB


High impact information on M-3-OB

  • M-2-OB, although given in significantly smaller doses (minimum dose, 2.3 mg/kg body weight) than was M-3-OB (minimum dose, 17.6 mg/kg body weight), induced a much broader spectrum of neoplasms (in 17 tissues), whereas M-3-OB induced tumors in only 5 tissues and had no carcinogenic effect in the pancreas [1].


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