Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Isodityrosine (2S)-2-amino-3-[4-[5-(2- amino-2-carboxy...

Synonyms: AG-H-32119, KST-1A8708, AC1Q5QKQ, CTK3D4527, AR-1A3217, ...

Fry, S.C., Brady, J.D. et al., Sano, S. et al., Waffenschmidt, S. et al.

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High impact information on Isodityrosine

Isodityrosine cross-linking mediates insolubilization of cell walls in Chlamydomonas [1].
2. The amount of isodityrosine in sodium dodecyl sulphate-insoluble cell-wall preparations was proportional to the amount of hydroxyproline [2].
UV-absorption, fluorescence and 1H NMR spectra showed that the trimer was pulcherosine, composed of isodityrosine and tyrosine oxidatively coupled via a biphenyl linkage such that the aromatic core is 2,2'-dihydroxy-3-phenoxybiphenyl [3].
Most of the radioactivity of L-[14C]tyrosine was found in the 4-methylisodityrosine (B2) or isodityrosine (B1) moieties, and that of L-[14C]asparagine was in the beta-hydroxyasparagine moiety [4].

Associations of Isodityrosine with other chemical compounds

4. Dithiothreitol inhibited isodityrosine synthesis in vivo, and suppressed in parallel the covalent binding of newly synthesized protein in the cell wall [2].

References

Isodityrosine cross-linking mediates insolubilization of cell walls in Chlamydomonas. Waffenschmidt, S., Woessner, J.P., Beer, K., Goodenough, U.W. Plant Cell (1993) [Pubmed]
Isodityrosine, a new cross-linking amino acid from plant cell-wall glycoprotein. Fry, S.C. Biochem. J. (1982) [Pubmed]
Pulcherosine, an oxidatively coupled trimer of tyrosine in plant cell walls: its role in cross-link formation. Brady, J.D., Sadler, I.H., Fry, S.C. Phytochemistry (1998) [Pubmed]
OF4949, new inhibitors of aminopeptidase B. III. Biosynthesis. Sano, S., Ueno, M., Katayama, K., Nakamura, T., Obayashi, A. J. Antibiot. (1986) [Pubmed]

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