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Chemical Compound Review:

TETRABUTYLTIN tetrabutylstannane

Synonyms: Tin tetrabutyl, T6008_ALDRICH, ACMC-1C25D, CCRIS 6322, AG-D-90303, ...

Liu, S.M. et al., Heidrich, D.D. et al., Nakagomi, M. et al., Ema, M. et al., Rosenberg, D.W. et al.

Liu, Hsia, Huang, Heidrich, Steckelbroeck, Klingmuller,

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Disease relevance of tetrabutylstannane

Comparative developmental toxicity of di-, tri- and tetrabutyltin compounds after administration during late organogenesis in rats [1].

High impact information on tetrabutylstannane

Furthermore, the effects produced by tetra-n-butyltin on cytochrome P-450 at 24 hr were localized in the intestinal epithelium [2].
Therefore, we examined the effects of the organotin compounds tetrabutyltin (TTBT), TBT, dibutyltin dichloride (DBT) and monobutyltin trichloride (MBT) on human placental aromatase activity [3].
Butyltin residues (monobutyltin, MBT; dibutyltin, DBT; tributyltin, TBT; tetrabutyltin, TeBT) in the sea water and in the cobia (Rachycentron canadum) from aquaculture sites located offshore of Penhu island, Taiwan, were collected and quantified [4].
The ranking for efficiency on microtubule disruption was (TBC falling dots DBD) > (E(2) = TBT) > (BPA = alkylphenols, NP and OP) >> (phthalate esters, BBP, DHP, and DBP) [5].

References

Comparative developmental toxicity of di-, tri- and tetrabutyltin compounds after administration during late organogenesis in rats. Ema, M., Kurosaka, R., Amano, H., Ogawa, Y. Journal of applied toxicology : JAT. (1996) [Pubmed]
Actions of orally administered organotin compounds on heme metabolism and cytochrome P-450 content and function in intestinal epithelium. Rosenberg, D.W., Kappas, A. Biochem. Pharmacol. (1989) [Pubmed]
Inhibition of human cytochrome P450 aromatase activity by butyltins. Heidrich, D.D., Steckelbroeck, S., Klingmuller, D. Steroids (2001) [Pubmed]
Accumulation of butyltin compounds in cobia Rachycentron canadum raised in offshore aquaculture sites. Liu, S.M., Hsia, M.P., Huang, C.M. Sci. Total Environ. (2006) [Pubmed]
Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats. Nakagomi, M., Suzuki, E., Usumi, K., Saitoh, Y., Yoshimura, S., Nagao, T., Ono, H. Teratog., Carcinog. Mutagen. (2001) [Pubmed]

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