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Chemical Compound Review:

AG-G-14947 3-(2-methoxyphenyl)prop-2-enal

Synonyms: ANW-21281, CTK5B1017, CTK8B0829, KSC910Q2T, KB-173546, ...

Guo, J.Y. et al., Reddy, A.M. et al., Hasegawa, A. et al.

Hasegawa, Yoshino, Nakamura, Ishii, Watanabe, Kiuchi, Ishikawa, Ohmori, Kitada,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on O-METHOXYCINNAMALDEHYDE

Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia [1].
The aim of the present study was to investigate the effects of 2-methoxycinnamaldehyde on PGE(2) production of rat cerebral endothelial cells (CECs) [2].
The component inhibiting drug oxidations catalyzed by CYP1A2 and CYP2E1 was isolated from Cinnamomi Cortex, and was identified as o-methoxycinnamaldehyde (OMCA) [3].

Associations of O-METHOXYCINNAMALDEHYDE with other chemical compounds

Both trans-cinnamaldehyde and 2-methoxycinnamaldehyde inhibited LPS-induced DNA binding activity of NF-KB in addition to NF-KB transcription-al activity [1].
2-Methoxycinnamaldehyde Reduces IL-1beta-Induced Prostaglandin Production in Rat Cerebral Endothelial Cells [2].

References

Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia. Reddy, A.M., Seo, J.H., Ryu, S.Y., Kim, Y.S., Kim, Y.S., Min, K.R., Kim, Y. Planta Med. (2004) [Pubmed]
2-Methoxycinnamaldehyde Reduces IL-1beta-Induced Prostaglandin Production in Rat Cerebral Endothelial Cells. Guo, J.Y., Huo, H.R., Yang, Y.X., Li, C.H., Liu, H.B., Zhao, B.S., Li, L.F., Ma, Y.Y., Guo, S.Y., Jiang, T.L. Biol. Pharm. Bull. (2006) [Pubmed]
Identification of inhibitory component in cinnamon--O-methoxycinnamaldehyde inhibits CYP1A2 and CYP2E1-. Hasegawa, A., Yoshino, M., Nakamura, H., Ishii, I., Watanabe, T., Kiuchi, M., Ishikawa, T., Ohmori, S., Kitada, M. Drug Metab. Pharmacokinet. (2002) [Pubmed]

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