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MeSH Review


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Disease relevance of Cassia


High impact information on Cassia


Chemical compound and disease context of Cassia


Biological context of Cassia


Anatomical context of Cassia


Associations of Cassia with chemical compounds

  • Anthraquinone pigments from cassia occidentalis [21].
  • Antinociceptive profile of (-)-spectaline: a piperidine alkaloid from Cassia leptophylla [22].
  • The results obtained are useful as a step towards standardisation of allergen extracts of Cassia species and are also worthy of further investigations both in relation to cross-reactivity and characterisation of allergens [23].
  • In this study, we evaluated the antimutagenic effect of C. cassia against two mutagens, viz. benzo[a]pyrene (B[a]P) and cyclophosphamide (CP) [24].
  • C. cassia pretreatment decreased Cyt P450 content but increased GSH content and the activity of glutathione-dependent antioxidant enzymes, viz [24].

Gene context of Cassia

  • Significant increase in the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and reduced glutathione were observed in brain on treatment with Cassia auriculata flower extract (CFEt) and glibenclamide [25].
  • 2'-Hydroxycinnamaldehyde (HCA) was isolated from Cinnamomum cassia Blume (Lauraceae) and 2'-benzoyloxycinnamaldehyde (BCA) was prepared by the reaction of HCA and benzoyl chloride [26].
  • Antioxidant effects of extracts from Cassia tora L. prepared under different degrees of roasting on the oxidative damage to biomolecules [27].
  • Antiallergic agent from natural sources. 2. Structures and leukotriene release-inhibitory effect of torososide B and torosachrysone 8-O-6"-malonyl beta-gentiobioside from Cassia torosa Cav [28].
  • Cassia gum is approved for use in Europe by the Commission Directive (EEC No. E 499) and is listed in the Annex of the Council Directive (70/524/EEC) as a stabilizer (thickening and gelling agent) in the manufacture of canned pet foods (for cats and dogs) [29].

Analytical, diagnostic and therapeutic context of Cassia


  1. Antioxidant activities of phenolic, proanthocyanidin, and flavonoid components in extracts of Cassia fistula. Luximon-Ramma, A., Bahorun, T., Soobrattee, M.A., Aruoma, O.I. J. Agric. Food Chem. (2002) [Pubmed]
  2. Antibacterial activity of extracts from some edible plants commonly consumed in Asia. Alzoreky, N.S., Nakahara, K. Int. J. Food Microbiol. (2003) [Pubmed]
  3. The value of a mixture of cassia and citronella oils for detection of hypersensitivity of essential oils. Rudzki, E., Grzywa, Z. Dermatosen in Beruf und Umwelt. Occupation and environment. (1985) [Pubmed]
  4. Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats. Pari, L., Latha, M. Singapore medical journal. (2002) [Pubmed]
  5. Barakol extracted from Cassia siamea stimulates chloride secretion in rat colon. Deachapunya, C., Poonyachoti, S., Thongsaard, W., Krishnamra, N. J. Pharmacol. Exp. Ther. (2005) [Pubmed]
  6. Salicylic acid-induced aluminum tolerance by modulation of citrate efflux from roots of Cassia tora L. Yang, Z.M., Wang, J., Wang, S.H., Xu, L.L. Planta (2003) [Pubmed]
  7. Molecular characterization of root-specific chalcone synthases from Cassia alata. Samappito, S., Page, J., Schmidt, J., De-Eknamkul, W., Kutchan, T.M. Planta (2002) [Pubmed]
  8. Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia. Reddy, A.M., Seo, J.H., Ryu, S.Y., Kim, Y.S., Kim, Y.S., Min, K.R., Kim, Y. Planta Med. (2004) [Pubmed]
  9. Biochemical modes of action of Cassia occidentalis and Cardiospermum halicacabum in inflammation. Sadique, J., Chandra, T., Thenmozhi, V., Elango, V. Journal of ethnopharmacology. (1987) [Pubmed]
  10. Effect of Cassia alata leaf extract on hyperglycemic rats. Palanichamy, S., Nagarajan, S., Devasagayam, M. Journal of ethnopharmacology. (1988) [Pubmed]
  11. Cassia senna inhibits mutagenic activities of benzo[a]-pyrene, aflatoxin B1, shamma and methyl methanesulfonate. al-Dakan, A.A., al-Tuffail, M., Hannan, M.A. Pharmacol. Toxicol. (1995) [Pubmed]
  12. A new biologically active flavone glycoside from the seeds of Cassia fistula (Linn.). Yadava, R.N., Verma, V. Journal of Asian natural products research. (2003) [Pubmed]
  13. Antioxidant activity of Cassia fistula (Linn.) flowers in alloxan induced diabetic rats. Manonmani, G., Bhavapriya, V., Kalpana, S., Govindasamy, S., Apparanantham, T. Journal of ethnopharmacology. (2005) [Pubmed]
  14. Genetic identification of cinnamon (Cinnamomum spp.) based on the trnL-trnF chloroplast DNA. Kojoma, M., Kurihara, K., Yamada, K., Sekita, S., Satake, M., Iida, O. Planta Med. (2002) [Pubmed]
  15. Seasonal variations of hydroxyanthraquinone content of cultivated Cassia spectabilis DC. Abo, K.A., Adeyemi, A.A., Sobowale, A.O. African journal of medicine and medical sciences. (2000) [Pubmed]
  16. Protective effect of Cassia occidentalis L. on cyclophosphamide-induced suppression of humoral immunity in mice. Bin-Hafeez, B., Ahmad, I., Haque, R., Raisuddin, S. Journal of ethnopharmacology. (2001) [Pubmed]
  17. Antioxidant activity of Cinnamomum cassia. Lin, C.C., Wu, S.J., Chang, C.H., Ng, L.T. Phytotherapy research : PTR. (2003) [Pubmed]
  18. The inhibitory effect of 3,3',4,5'-tetrahydroxystilbene, a constituent of Cassia garrettiana, on anti-IgE-induced histamine release from human basophils in vitro. Inamori, Y., Ogawa, M., Tsujibo, H., Baba, K., Kozawa, M., Nakamura, H. Chem. Pharm. Bull. (1991) [Pubmed]
  19. Inhibitory effects of 3,3',4,5'-tetrahydroxystilbene and 3,3',4,5'-tetrahydroxybibenzyl, the constituents of Cassia garrettiana on antigen-induced histamine release in vitro. Inamori, Y., Ogawa, M., Tsujibo, H., Baba, K., Kozawa, M., Nakamura, H. Chem. Pharm. Bull. (1991) [Pubmed]
  20. The involvement of medullary reticular formation in the hypotensive effect of extracts from seeds of Cassia tora. Chan, S.H., Koo, A., Li, K.M. The American journal of Chinese medicine. (1976) [Pubmed]
  21. Anthraquinone pigments from cassia occidentalis. Tiwari, R.D., Singh, J. Planta Med. (1977) [Pubmed]
  22. Antinociceptive profile of (-)-spectaline: a piperidine alkaloid from Cassia leptophylla. Alexandre-Moreira, M.S., Viegas, C., Palhares de Miranda, A.L., Bolzani, V.d.a. .S., Barreiro, E.J. Planta Med. (2003) [Pubmed]
  23. Studies on Cassia pollen grains of India. Satheesh, R., Prakashkumar, R., Jose, J.C., Nair, P.K., Rao, G.R. Int. Arch. Allergy Immunol. (1994) [Pubmed]
  24. Inhibition of benzo[a]pyrene- and cyclophoshamide-induced mutagenicity by Cinnamomum cassia. Sharma, N., Trikha, P., Athar, M., Raisuddin, S. Mutat. Res. (2001) [Pubmed]
  25. Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin. Latha, M., Pari, L. Mol. Cell. Biochem. (2003) [Pubmed]
  26. Inhibition of human tumor growth by 2'-hydroxy- and 2'-benzoyloxycinnamaldehydes. Lee, C.W., Hong, D.H., Han, S.B., Park, S.H., Kim, H.K., Kwon, B.M., Kim, H.M. Planta Med. (1999) [Pubmed]
  27. Antioxidant effects of extracts from Cassia tora L. prepared under different degrees of roasting on the oxidative damage to biomolecules. Yen, G.C., Chung, D.Y. J. Agric. Food Chem. (1999) [Pubmed]
  28. Antiallergic agent from natural sources. 2. Structures and leukotriene release-inhibitory effect of torososide B and torosachrysone 8-O-6"-malonyl beta-gentiobioside from Cassia torosa Cav. Kanno, M., Shibano, T., Takido, M., Kitanaka, S. Chem. Pharm. Bull. (1999) [Pubmed]
  29. Assessment of cassia gum. Hallagan, J.B., La Du, B.N., Pariza, M.W., Putnam, J.M., Borzelleca, J.F. Food Chem. Toxicol. (1997) [Pubmed]
  30. Barakol: a potential anxiolytic extracted from Cassia siamea. Thongsaard, W., Deachapunya, C., Pongsakorn, S., Boyd, E.A., Bennett, G.W., Marsden, C.A. Pharmacol. Biochem. Behav. (1996) [Pubmed]
  31. Effects of cassia oil on serum and hepatic uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver. Zhao, X., Zhu, J.X., Mo, S.F., Pan, Y., Kong, L.D. Journal of ethnopharmacology. (2006) [Pubmed]
  32. An improved method for the analysis of sennosides in Cassia angustifolia by high-performance liquid chromatography. Bala, S., Uniyal, G.C., Dubey, T., Singh, S.P. Phytochemical analysis : PCA. (2001) [Pubmed]
  33. Separation and determination of anthraquinones in Cassia obtusifolia (Leguminosae) by micellar electrokinetic capillary electrophoresis. Jiang, T.F., Lv, Z.H., Wang, Y.H. Journal of separation science. (2005) [Pubmed]
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