Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

HMDB06409 1-(2-aminoethyl)-4-sulfooxy- benzene

Synonyms: AC1L49IP, 30223-92-8, Tyramine-O-sulfate, Tyramine O-sulfate, 1-(2-AMINOETHYL)-4-SULFOOXY-BENZENE, ...

Liu, M.C. et al., Harrison, W.M. et al.

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High impact information on Tyramine O-sulfate

A previous study reported that unipolar depressives excrete significantly lower amounts of urinary tyramine-O-sulfate following oral administration of a tyramine hydrochloride load than do normal control subjects [1].
Endogenous aromatic amino acid decarboxylase present in HepG2 homogenate was shown to catalyze the decarboxylation of [3H]tyrosine to form [3H]tyramine while attempts to use it for the decarboxylation of tyrosine-O-sulfate to form tyramine-O-sulfate were unsuccessful [2].

References

The tyramine challenge test as a marker for melancholia. Harrison, W.M., Cooper, T.B., Stewart, J.W., Quitkin, F.M., McGrath, P.J., Liebowitz, M.R., Rabkin, J.R., Markowitz, J.S., Klein, D.F. Arch. Gen. Psychiatry (1984) [Pubmed]
Tyramine-O-sulfate, in addition to tyrosine-O-sulfate, is produced and secreted by HepG2 human hepatoma cells, but not by 3Y1 rat embryo fibroblasts. Liu, M.C., Yu, S., Suiko, M. Biochem. Int. (1990) [Pubmed]

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