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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Prochloraz Mn     dichloromanganese; N-propyl-N-[2-(2,4,6...

Synonyms: CQ 1054, AC1L4DT0, 69192-23-0, EINECS 273-907-4, Prochloraz manganese complex
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Disease relevance of Prelude

  • Two protocols ("Octave" and "Binary") were developed, each of which was patterned after the testing procedure previously developed at the Oregon Tinnitus Clinic and used to assess thousands of tinnitus patients [1].
  • The clinical features of Guillain-Barré syndrome were initially described by Octave Landry in 1859 [2].
  • In this study, the authors examined motion sickness symptoms among 119 passengers and 100 conductors of both trains with a self-administered questionnaire, and evaluated the vibration acceleration on the floor by using the 1/3 Octave Band Analyzer and the Fast Fourier Transform method (FFT) [3].

High impact information on Prelude

  • It is shown experimentally that the motion of the tectorial membrane is resonant at a frequency of 0.5 octave (oct) below the resonant frequency of the basilar membrane and polarized parallel to the reticular lamina [4].
  • Comparative effect of the fungicide Prochloraz-Mn on Agaricus bisporus vegetative-mycelium and fruit-body cell walls [5].
  • Furthermore, the aggregated mycelial walls showed distinct alterations in their overall chemical composition following the administration of Prochloraz-Mn at the LD50 and the LD50 x1000 [5].

Anatomical context of Prelude


  1. Comparison of two computer-automated procedures for tinnitus pitch matching. Henry, J.A., Flick, C.L., Gilbert, A., Ellingson, R.M., Fausti, S.A. Journal of rehabilitation research and development. (2001) [Pubmed]
  2. Octave Landry: Guillain-Barré syndrome. Brody, A.J., Sternbach, G., Varon, J. The Journal of emergency medicine. (1994) [Pubmed]
  3. Studies on motion sickness caused by high curve speed railway vehicles. Evaluation of the swing and its effects on passengers and conductors. Ueno, M., Ogawa, T., Nakagiri, S., Arisawa, T., Mino, Y., Oyama, K., Kodera, R., Taniguchi, T., Kanazawa, S., Ohta, T. Sangyō igaku. Japanese journal of industrial health. (1986) [Pubmed]
  4. Resonant tectorial membrane motion in the inner ear: its crucial role in frequency tuning. Gummer, A.W., Hemmert, W., Zenner, H.P. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  5. Comparative effect of the fungicide Prochloraz-Mn on Agaricus bisporus vegetative-mycelium and fruit-body cell walls. Bernardo, D., Pérez Cabo, A., Novaes-Ledieu, M., Pardo, J., García Mendoza, C. Int. Microbiol. (2004) [Pubmed]
  6. Effect of the fungicide Prochloraz-Mn on the cell wall structure of Verticillium fungicola. Bernardo, D., Novaes-Ledieu, M., Perez Cabo, A., Gea Alegría, F.J., García Mendoza, C. Int. Microbiol. (2002) [Pubmed]
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