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Chemical Compound Review

Coryneine     2-(3,4-dihydroxyphenyl)ethyl- trimethyl...

Synonyms: SureCN4824806, AC1L4WWC, AC1Q7ACS, AR-1C7091, C17486, ...
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High impact information on NSC42278

  • The activity of m-hydroxybenzyltrimethylammonium, coryneine (3:4-dihydroxyphenethyltrimethylammonium, 'quaternary dopamine'), and m-hydroxyphenylpropyltrimethylammonium relative to tetramethylammonium has been measured on the frog rectus preparation (Rana pipiens) at pH 7 and pH 9 [1].
  • These results suggest that of the two components contained in aconite root, higenamine increases ACh release via activation of beta-adrenoceptor, and conversely coryneine depresses ACh release by preferentially acting at motor nerve terminal [2].

Analytical, diagnostic and therapeutic context of NSC42278


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