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Chemical Compound Review

CHEMBL46486     tetramethylazanium

Synonyms: AGN-PC-008DGT, CPD-7679, CHEBI:46020, bmse000780, NSC-102944, ...
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Disease relevance of tetramethylammonium


High impact information on tetramethylammonium


Chemical compound and disease context of tetramethylammonium


Biological context of tetramethylammonium


Anatomical context of tetramethylammonium


Associations of tetramethylammonium with other chemical compounds


Gene context of tetramethylammonium

  • The largest permeant ion, tetramethylammonium with a diameter of 0.55 nm, had PTMA/PNa of 0.09 [27].
  • All three antibodies were raised against the same antigen, human erythrocyte AChE, a commercial product purified using the cholinesterase anionic site inhibitor, tetramethylammonium [28].
  • Rat VAChT was expressed in PC12(A1237) cells, postnuclear supernatant-containing microvesicles was prepared, and the reorientation assay was conducted with unlabeled Ch and tetramethylammonium (TMA) [29].
  • Control experiments with fluorescent dextran of similar molecular weight and tetramethylammonium confirmed EGF did not affect local ECS structure [30].
  • ECS tortuosity lambda = (D/ADC)0.5, where D is the free diffusion coefficient and ADC is the apparent diffusion coefficient of TMA+ in the brain, increases as measured perpendicular to the axons from 1.53 +/- 0.02 (n = 6, mean +/- SEM) to 1.70 +/- 0.02 (n = 6) [31].

Analytical, diagnostic and therapeutic context of tetramethylammonium


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