Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

Avafortan disodium;[(1,5-dimethyl-3- oxo-2-phenyl...

Synonyms: Avapyrazone, AG-K-64730, CTK0H7602, AR-1L5358, AC1L4Z2M, ...

Lee, Y.H. et al., el-Sherif, A.E. et al., Fosseus, C.G. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Avapyrazone

Our results showed that acupuncture is as effective in relieving renal colic as Avafortan but it had a more rapid analgesic onset (3.14 +/- 2.88 minutes versus 15.44 +/- 7.55 minutes, p less than 0.05) [1].
However, patients receiving Avafortan treatment were more likely to have paralytic ileus [1].
Of the patients in the Avafortan group 7 (43.8%) had side effects, including skin rash in 3, tachycardia in 2, drowsiness in 1 and facial flush in 1 [1].
Sudden death due to intravenous avapyrazone and dipyrone [2].

High impact information on Avapyrazone

A prospective randomized study was performed to compare the effect of acupuncture and intramuscular Avafortan injection in the treatment of renal colic [1].

Chemical compound and disease context of Avapyrazone

Treatment of renal colic by prostaglandin synthetase inhibitors and avafortan (analgesic antispasmodic) [3].

Biological context of Avapyrazone

During 2 hours of observation acupuncture and Avafortan seemed to be ineffective in promoting stone passage [1].

References

Acupuncture in the treatment of renal colic. Lee, Y.H., Lee, W.C., Chen, M.T., Huang, J.K., Chung, C., Chang, L.S. J. Urol. (1992) [Pubmed]
Sudden death due to intravenous avapyrazone and dipyrone. Fosseus, C.G., Straughan, J.L. S. Afr. Med. J. (1983) [Pubmed]
Treatment of renal colic by prostaglandin synthetase inhibitors and avafortan (analgesic antispasmodic). el-Sherif, A.E., Foda, R., Norlen, L.J., Yahia, H. British journal of urology. (1990) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg