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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

CCRIS 8223     2-[[3,5,5-trimethyl-6-[2-(2- methylprop-2...

Synonyms: LS-188753, FT-0667734, AC1L55NH, 436909_ALDRICH, 41137-60-4, ...
 
 
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High impact information on EINECS 255-239-5

  • Purified T-lymphocytes stimulated by pulpal cells did not show enhanced responses to UDMA, bis-GMA, glycidyl mehtacrylate (GMA), or N,N,-dihydroxyethyl-p-toluidine (DHEpT) [1].
  • The monomers include bis-phenol A glycidyl dimethacrylate (bis-GMA), urethane dimethacrylate (UDMA) and triethylene glycol dimethacrylate (TEGDMA) as a viscosity modifier [2].
  • The replacement of TEGDMA with urethane dimethacrylate (UDMA) and Bis-EMA in Filtek Z250 and P60, decreases the polymerisation shrinkage stress by increasing the cross-linking of polymer networks [3].
  • At higher concentrations of up to 2.5x10(-2) induced DNA migration was expressed by OTM of 3.3 for HEMA, 4.5 for TEGDMA, 7.4 for Bis-GMA, and 2.8 for UDMA [4].
  • Two-way analysis of variance showed significant correlations between MMA, HEMA, EGDMA or TEGDMA and UDMA or Bis-GMA (P<.01) [5].
 

Anatomical context of EINECS 255-239-5

  • Resin components suppressed the mitochondrial activity of macrophages at different concentrations (TC50 values for HEMA (10,000 mumol/L), 4-META (3,800 mumol/L), Bis-GMA (130 mumol/L), and UDMA (110 mumol/L) at 24 h, and the effect was time-dependent [6].
 

Gene context of EINECS 255-239-5

  • A urethane dimethacrylate (UDMA) microfilled composite bonded weakly to BIS-GMA composite, therefore their combined use should be avoided [7].
 

Analytical, diagnostic and therapeutic context of EINECS 255-239-5

References

  1. Effects of unpolymerized resin components on the function of accessory cells derived from the rat incisor pulp. Jontell, M., Hanks, C.T., Bratel, J., Bergenholtz, G. J. Dent. Res. (1995) [Pubmed]
  2. Development of high-viscosity, two-paste bioactive bone cements. Deb, S., Aiyathurai, L., Roether, J.A., Luklinska, Z.B. Biomaterials (2005) [Pubmed]
  3. Cuspal movement and microleakage in premolar teeth restored with posterior filling materials of varying reported volumetric shrinkage values. Fleming, G.J., Hall, D.P., Shortall, A.C., Burke, F.J. Journal of dentistry. (2005) [Pubmed]
  4. Genotoxicity and cytotoxicity of dental materials in human lymphocytes as assessed by the single cell microgel electrophoresis (comet) assay. Kleinsasser, N.H., Wallner, B.C., Harréus, U.A., Kleinjung, T., Folwaczny, M., Hickel, R., Kehe, K., Reichl, F.X. Journal of dentistry. (2004) [Pubmed]
  5. Monomer permeability of disposable dental gloves. Nakamura, M., Oshima, H., Hashimoto, Y. The Journal of prosthetic dentistry. (2003) [Pubmed]
  6. Effects of dentin bonding agents on macrophage mitochondrial activity. Rakich, D.R., Wataha, J.C., Lefebvre, C.A., Weller, R.N. Journal of endodontics. (1998) [Pubmed]
  7. A urethane dimethacrylate (UDMA) microfilled composite bonded weakly to BIS-GMA composite, therefore their combined use should be avoided. Rueggerberg, F.A. The Journal of prosthetic dentistry. (1989) [Pubmed]
  8. Use of a light-polymerized composite removable partial denture base for a patient hypersensitive to poly(methyl methacrylate), polysulfone, and polycarbonate: a clinical report. Tanoue, N., Nagano, K., Matsumura, H. The Journal of prosthetic dentistry. (2005) [Pubmed]
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