The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

Table of contents

About

Terms

 

Chemical Compound Review: 

MT-100     sodium; 4-amino-5-chloro-N-(2...

Synonyms: AC1L4USX, AC1Q1VQX, AR-1L5344, MT 100
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of MT-100

  • The level of TAA was high in 2 metastatic carcinomas tested (TMT-081 and SMT-2A) and much lower--by a factor of 50--200--in 2 nonmetastatic mammary carcinomas (MT-100 and MT-W9B) [1].
  • POZEN has three other compounds, MT-400, MT-300 and MT-100, in phases I, II and III, respectively, for the treatment of acute migraine [2].
  • Cell line MT-100-TC is a line derived from the ascites of a rat bearing the ascites form of MT-100 [3].
 

High impact information on MT-100

  • Fucosyltransferase levels in 6 established strains of spontaneously metastasizing rat mammary tumors (STMT-058, MT-449, DMBA-4, SMT-077, TMT-081, and SMT-2A) were compared with 4 nonmetastasizing strains (MT-W9B, MT-W9A, MT-100, and MT-66) as controls [4].
  • Two continuous rat mammary tumor cell lines have been established in culture from the lymphogenously metastasizing rat mammary carcinoma TMT-081 and one from the nonmetastasizing MT-100 and some of their in vitro and in vivo characteristics studied [3].

References

  1. A tumor-associated organ-specific antigen characteristic of spontaneously metastatic rat mammary carcinomas. Ghosh, S.K., Grossberg, A.L., Kim, U., Pressman, D. J. Natl. Cancer Inst. (1979) [Pubmed]
  2. MT-500 (POZEN). Mucke, H.A. Current opinion in investigational drugs (London, England : 2000) (2001) [Pubmed]
  3. Establishment of two nonmetastasizing and one metastasizing rat mammary carcinoma cell lines. Ghosh, S.K., Roholt, O.A., Kim, U. In vitro. (1983) [Pubmed]
  4. Fucosyltransferase activity in metastasizing and nonmetastasizing rat mammary carcinomas. Chatterjee, S.K., Kim, U. J. Natl. Cancer Inst. (1978) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities