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Chemical Compound Review:

Aceglutamid 2-acetamido-4-aminocarbonyl- butanoic acid

Synonyms: Aceglutamida, Aceglutamide, Aceglutamidum, Acutil-S, ACMC-209gfh, ...

Arnaud, A. et al., Bergana, M.M. et al., Tanaka, H. et al.

Bergana, Holton, Reyzer, Snowden, Baxter, Pound,

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Disease relevance of Acetylglutamine

Effect of N-acetyl-L-glutamine aluminum complex (KW-110), an antiulcer agent, on the non-steroidal anti-inflammatory drug-induced exacerbation of gastric ulcer in rats [1].

High impact information on Acetylglutamine

(1) In a clamped jejunal loop experiment, we measured the concentrations of glutamine and N-acetyl-l-glutamine in the intestinal infused solutions, intestinal mucosa, and portal and peripheral blood [2].
CONCLUSION: N-acetyl-l-glutamine appeared to be a good candidate for glutamine fortification of enteral nutrition formulas [2].
One-dimensional proton and proton-decoupled carbon-13 NMR and electrospray LC-MS/MS techniques were employed to identify the molecular structures of the generated N-acetyl-L-glutamine decomposition products [3].

References

Effect of N-acetyl-L-glutamine aluminum complex (KW-110), an antiulcer agent, on the non-steroidal anti-inflammatory drug-induced exacerbation of gastric ulcer in rats. Tanaka, H., Shuto, K., Marumo, H. Jpn. J. Pharmacol. (1982) [Pubmed]
Absorption of enterally administered N-acetyl-l-glutamine versus glutamine in pigs. Arnaud, A., Ramírez, M., Baxter, J.H., Angulo, A.J. Clinical nutrition (Edinburgh, Scotland) (2004) [Pubmed]
NMR and MS analysis of decomposition compounds produced from N-acetyl-L-glutamine at low pH. Bergana, M.M., Holton, J.D., Reyzer, I.L., Snowden, M.K., Baxter, J.H., Pound, V.L. J. Agric. Food Chem. (2000) [Pubmed]

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