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Chemical Compound Review

PubChem10617     (2R)-2-amino-3-(1- methylindol-3...

Synonyms: CHEMBL571209, SureCN934800, NLG-8189, AG-D-27346, NSC-721782, ...
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High impact information on NSC721782


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Gene context of NSC721782

  • Furthermore, addition of IDO-inhibitor (1-methyl-d-tryptophan) reversed the suppressive effects of IDO on PBMC proliferation in a dose-dependant fashion [7].


  1. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. Munn, D.H., Sharma, M.D., Hou, D., Baban, B., Lee, J.R., Antonia, S.J., Messina, J.L., Chandler, P., Koni, P.A., Mellor, A.L. J. Clin. Invest. (2004) [Pubmed]
  2. Synovial Autoreactive T Cells in Rheumatoid Arthritis Resist IDO-Mediated Inhibition. Zhu, L., Ji, F., Wang, Y., Zhang, Y., Liu, Q., Zhang, J.Z., Matsushima, K., Cao, Q., Zhang, Y. J. Immunol. (2006) [Pubmed]
  3. Indoleamine 2,3-dioxygenase participates in the interferon-gamma-induced cell death process in cultured bovine luteal cells. Cannon, M.J., Pate, J.L. Biol. Reprod. (2006) [Pubmed]
  4. Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. Potula, R., Poluektova, L., Knipe, B., Chrastil, J., Heilman, D., Dou, H., Takikawa, O., Munn, D.H., Gendelman, H.E., Persidsky, Y. Blood (2005) [Pubmed]
  5. Proliferation of peripheral blood mononuclear cells is suppressed by the indoleamine 2,3-dioxygenase expression of interferon-gamma-treated skin cells in a co-culture system. Sarkhosh, K., Tredget, E.E., Li, Y., Kilani, R.T., Uludag, H., Ghahary, A. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. (2003) [Pubmed]
  6. Temperature-sensitive polymer-conjugated IFN-gamma induces the expression of IDO mRNA and activity by fibroblasts populated in collagen gel (FPCG). Sarkhosh, K., Tredget, E.E., Uludag, H., Kilani, R.T., Karami, A., Li, Y., Iwashina, T., Ghahary, A. J. Cell. Physiol. (2004) [Pubmed]
  7. Immune cell proliferation is suppressed by the interferon-gamma-induced indoleamine 2,3-dioxygenase expression of fibroblasts populated in collagen gel (FPCG). Sarkhosh, K., Tredget, E.E., Karami, A., Uludag, H., Iwashina, T., Kilani, R.T., Ghahary, A. J. Cell. Biochem. (2003) [Pubmed]
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