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Chemical Compound Review:

Pretyrosine 1-[(2S)-2-amino-2-carboxy- ethyl]-4-hydroxy...

Synonyms: SureCN321854, CHEBI:17530, AC1L974H, C00826, 53078-86-7, ...

Zamir, L.O. et al., Byng, G.S. et al., Keller, B. et al.

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Disease relevance of L-Arogenic acid

Enzymatic and nonenzymatic dehydration reactions of L-arogenate [1].
Arogenate (pretyrosine) pathway of tyrosine and phenylalanine biosynthesis in Pseudomonas aureofaciens ATCC 15926 [2].

High impact information on L-Arogenic acid

L-Tyrosine inhibited activity effectively with kinetics that were competitive with respect to L-arogenate and noncompetitive with respect to nicotinamide adenine dinucleotide phosphate [3].
An improved assay is described for this in which [3H]dansyl derivatives of L-arogenate (substrate) and L-phenylalanine (product) are separated by using bidimensional thin-layer chromatography [1].

References

Enzymatic and nonenzymatic dehydration reactions of L-arogenate. Zamir, L.O., Tiberio, R., Fiske, M., Berry, A., Jensen, R.A. Biochemistry (1985) [Pubmed]
Arogenate (pretyrosine) pathway of tyrosine and phenylalanine biosynthesis in Pseudomonas aureofaciens ATCC 15926. Keller, B., Keller, E., Salcher, O., Lingens, F. J. Gen. Microbiol. (1982) [Pubmed]
The aromatic amino acid pathway branches at L-arogenate in Euglena gracilis. Byng, G.S., Whitaker, R.J., Shapiro, C.L., Jensen, R.A. Mol. Cell. Biol. (1981) [Pubmed]

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