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Chemical Compound Review:

ferulate (E)-3-(4-hydroxy-3-methoxy- phenyl)prop-2...

Synonyms: trans-Ferulate, Coniferic acid, PubChem8183, Fumalic acid, ferulic acid, ...

Faulds, C.B. et al., Nesci, A.V. et al., Vailhé, M.A. et al., Liang, Q.D. et al.

Faulds, Mandalari, Lo Curto, Bisignano, Christakopoulos, Waldron,

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Disease relevance of ferulate

Pae and FA showed significant body weight reducing effect, which were largely abolished when they were combined with Fru and TP [1].

High impact information on ferulate

The type A feruloyl esterase from Aspergillus niger, AnFaeA, works synergistically with (1-->4)-beta-D-xylopyranosidases (xylanases) to release monomeric and dimeric ferulic acid (FA) from cereal cell wall-derived material [2].
The esterase was more effective with a family 11 xylanase from Trichoderma viride in releasing FA and with a family 10 xylanase from Thermoascus aurantiacus in releasing the 5,5' form of diferulic acid from arabinoxylan (AX) derived from brewers' spent grain [2].
A positive relationship between Et & Et+Es FA was also found, with the rate (P < 0.01) being better correlated than the extent (P < 0.05) of cell wall degradation [3].
The effects of the natural phytochemicals trans-cinnamic acid (CA) and ferulic acid (FA) alone at concentrations of 1-25 mM and in 16 combinations (M: mixtures) on growth and aflatoxin B(1) production by Aspergillus flavus Link and A. parasiticus Speare were evaluated [4].

Associations of ferulate with other chemical compounds

The data show that CA and FA can be considered as effective fungitoxicants for A. flavus and A. parasiticus in in vitro assay [4].

References

Effects of four Si-Wu-Tang's constituents and their combination on irradiated mice. Liang, Q.D., Gao, Y., Tan, H.L., Guo, P., Li, Y.F., Zhou, Z., Tan, W., Ma, Z.C., Ma, B.P., Wang, S.Q. Biol. Pharm. Bull. (2006) [Pubmed]
Synergy between xylanases from glycoside hydrolase family 10 and family 11 and a feruloyl esterase in the release of phenolic acids from cereal arabinoxylan. Faulds, C.B., Mandalari, G., Lo Curto, R.B., Bisignano, G., Christakopoulos, P., Waldron, K.W. Appl. Microbiol. Biotechnol. (2006) [Pubmed]
Effect of phenolic structures on the degradability of cell walls isolated from newly extended apical internode of tall fescue (Festuca arundinacea Schreb.). Vailhé, M.A., Provan, G.J., Scobbie, L., Chesson, A., Maillot, M.P., Cornu, A., Besle, J.M. J. Agric. Food Chem. (2000) [Pubmed]
Control of Aspergillus growth and aflatoxin production using natural maize phytochemicals under different conditions of water activity. Nesci, A.V., Etcheverry, M.G. Pest Manag. Sci. (2006) [Pubmed]

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