The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

MOLI001322     3-(1-hydroxy-2-methylamino- propyl)phenol

Synonyms: AC1L9P66, [11C]mHED, [11C]HED, [11C]meta-Hydroxyephedrine, (1R, 2S)-[11C]meta-Hydroxyephedrine, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on MOLI001322

  • In ND rats, no difference in [11C]HED retention or norepinephrine content was detected in the proximal versus distal myocardium [1].
  • Images of the retention of [11C]HED taken from 50 to 60 min postinjection were used to differentiate sympathetically innervated and denervated regions of the left ventricle [2].
 

Anatomical context of MOLI001322

  • After 6 months, compared with ND rats, myocardial [11C]HED retention had declined in the proximal segments of STZ-D rats by only 9% (NS) compared with a 33% decrease in the distal myocardium (P < 0.05) [1].
 

Analytical, diagnostic and therapeutic context of MOLI001322

References

  1. Heterogeneous cardiac sympathetic denervation and decreased myocardial nerve growth factor in streptozotocin-induced diabetic rats: implications for cardiac sympathetic dysinnervation complicating diabetes. Schmid, H., Forman, L.A., Cao, X., Sherman, P.S., Stevens, M.J. Diabetes (1999) [Pubmed]
  2. PET imaging of oxidative metabolism abnormalities in sympathetically denervated canine myocardium. Hutchins, G.D., Chen, T., Carlson, K.A., Fain, R.L., Winkle, W., Vavrek, T., Mock, B.H., Zipes, D.P. J. Nucl. Med. (1999) [Pubmed]
  3. Evidence for regional catecholamine uptake and storage sites in the transplanted human heart by positron emission tomography. Schwaiger, M., Hutchins, G.D., Kalff, V., Rosenspire, K., Haka, M.S., Mallette, S., Deeb, G.M., Abrams, G.D., Wieland, D. J. Clin. Invest. (1991) [Pubmed]
  4. Synthesis and preliminary evaluation of carbon-11-meta-hydroxyephedrine: a false transmitter agent for heart neuronal imaging. Rosenspire, K.C., Haka, M.S., Van Dort, M.E., Jewett, D.M., Gildersleeve, D.L., Schwaiger, M., Wieland, D.M. J. Nucl. Med. (1990) [Pubmed]
  5. Cardiac retention of [11C]HED in genotyped long QT patients: a potential amplifier role for severity of the disease. Mazzadi, A.N., André-Fouët, X., Duisit, J., Gebuhrer, V., Costes, N., Chevalier, P., Rodriguez, C., Schott, J.J., Le Marec, H., Guicheney, P., Le Bars, D., Janier, M. Am. J. Physiol. Heart Circ. Physiol. (2003) [Pubmed]
 
WikiGenes - Universities