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Chemical Compound Review:

Deprenyl N-methyl-N-[(2R)-1- phenylpropan-2-yl]prop...

Synonyms: AC1NRAUQ, DB04677, DPK

Boland, A. et al., Zajaczkowski, W. et al.

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Psychiatry related information on Deprenyl

BRO and MOC exert the inhibitory activity, whereas DEP has an excitatory effect on the startle reaction [1].

High impact information on Deprenyl

It has been shown that the MAO (monoamine oxidase)-B inhibitor deprenyl (DPR, selegiline) protects some cell types against oxidative stress [2].
Rat hippocampal or cortical cultured cells were exposed either to 2 microM FeSO(4) alone or in the presence of PIR, DHP, BRO, DPR, MCL or TRO [2].

References

The effects of single and repeated administration of MAO inhibitors on acoustic startle response in rats. Zajaczkowski, W., Górka, Z. Polish journal of pharmacology. (1993) [Pubmed]
Pirlindole and dehydropirlindole protect rat cultured neuronal cells against oxidative stress-induced cell death through a mechanism unrelated to MAO-A inhibition. Boland, A., Gérardy, J., Mossay, D., Delapierre, D., Seutin, V. Br. J. Pharmacol. (2002) [Pubmed]

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