Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CEFPIRAMIDE SODIUM sodium(6R,7S)-7-[[2-(4- hydroxyphenyl)-2...

Synonyms:

Fukasawa, M. et al., Matsui, H. et al., Wexler, H. et al., Kato, M. et al., Nakagawa, K. et al.

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Disease relevance of cefpiramide

A remarkable feature of the spectrum of SM-1652 is its high activity against Pseudomonadaceae [1].
SM-1652 possessed a wide antibacterial spectrum which included activity against Pseudomonas aeruginosa [2].
SM-1652 was relatively stable to hydrolysis with plasmid-mediated penicillinases and cephalosporinases produced by gram-negative bacteria [1].
The in vitro activities of two new antimicrobial agents, apalcillin and cefpiramide (SM-1652), were evaluated against 324 strains of anaerobic bacteria [3].

High impact information on cefpiramide

Pharmacokinetics of cefpiramide (SM-1652) in humans [4].

Biological context of cefpiramide

The pharmacokinetics of SM-1652 were studied in mice, rats, rabbits, dogs, and rhesus monkeys [5].

Associations of cefpiramide with other chemical compounds

Pharmacokinetics of the cephalosporin SM-1652 in mice, rats, rabbits, dogs, and rhesus monkeys [5].

References

In vitro antibacterial activity of SM-1652, a new broad-spectrum cephalosporin with antipseudomonal activity. Fukasawa, M., Noguchi, H., Okuda, T., Komatsu, T., Yano, K. Antimicrob. Agents Chemother. (1983) [Pubmed]
Antibacterial activities of SM-1652 compared with those of other broad-spectrum cephalosporins. Kato, M., Inoue, M., Mitsuhashi, S. Antimicrob. Agents Chemother. (1982) [Pubmed]
Comparative in vitro activities of cefpiramide and apalcillin against anaerobic bacteria. Wexler, H., Carter, W.T., Harris, B., Finegold, S.M. Antimicrob. Agents Chemother. (1984) [Pubmed]
Pharmacokinetics of cefpiramide (SM-1652) in humans. Nakagawa, K., Koyama, M., Matsui, H., Ikeda, C., Yano, K., Nakatsuru, N., Yoshinaga, K., Noguchi, T. Antimicrob. Agents Chemother. (1984) [Pubmed]
Pharmacokinetics of the cephalosporin SM-1652 in mice, rats, rabbits, dogs, and rhesus monkeys. Matsui, H., Yano, K., Okuda, T. Antimicrob. Agents Chemother. (1982) [Pubmed]

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