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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Macaca mulatta

 
 
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Disease relevance of Macaca mulatta

 

Psychiatry related information on Macaca mulatta

 

High impact information on Macaca mulatta

  • We developed an AIDS vaccine based on attenuated VSV vectors expressing env and gag genes and tested it in rhesus monkeys [11].
  • When rhesus monkeys were infected with a form of cloned SIVmac239 having a premature stop signal at the 93rd codon of nef, revertants with a coding codon at this position quickly and universally came to predominate in the infected animals [12].
  • We evaluated the ability of neonatal porcine islets to engraft and restore glucose control in pancreatectomized rhesus macaques [13].
  • Successful DNA immunization against measles: neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles [14].
  • We demonstrate here that administration of a CD154-specific monoclonal antibody (hu5C8) allows for renal allotransplantation in outbred, MHC-mismatched rhesus monkeys without acute rejection [15].
 

Chemical compound and disease context of Macaca mulatta

 

Biological context of Macaca mulatta

 

Anatomical context of Macaca mulatta

 

Associations of Macaca mulatta with chemical compounds

 

Gene context of Macaca mulatta

  • A rhesus monkey model to characterize the role of gastrin-releasing peptide (GRP) in lung development. Evidence for stimulation of airway growth [34].
  • We previously identified a novel nonclassical MHC class I molecule, Mamu-AG, which is expressed in the rhesus monkey placenta and shares many unique characteristics of HLA-G [35].
  • KD values of ezetimibe glucuronide for mouse, rat, rhesus monkey, and human NPC1L1 are 12,000, 540, 40, and 220 nM, respectively [36].
  • The administration of a CEA recombinant vaccine to rhesus monkeys induces both a humoral and a cell-mediated immune response directed against human CEA [37].
  • Taken together, these data suggest that convergent evolution may have resulted in the expression of a unique nonclassical MHC class I molecule in the rhesus monkey placenta, and that the common structural features of Mamu-AG and HLA-G may be functionally significant [38].
 

Analytical, diagnostic and therapeutic context of Macaca mulatta

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