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Chemical Compound Review

SureCN1650490     (2R,5R)-3,3-dimethyl-7-oxo-6- [[(2R)-2-[(4...

Synonyms: KST-1A7090, AC1Q5QXW, CTK8E0285, AR-1A3539, LS-149887, ...
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Disease relevance of Apalcillin


High impact information on Apalcillin


Chemical compound and disease context of Apalcillin


Biological context of Apalcillin


Anatomical context of Apalcillin


Gene context of Apalcillin


Analytical, diagnostic and therapeutic context of Apalcillin


  1. Activity of apalcillin against Pseudomonas aeruginosa. Hollick, G.E., Gundrum, J., Venezia, R.A. Antimicrob. Agents Chemother. (1984) [Pubmed]
  2. In vitro activity of apalcillin compared with that of other new penicillins and anti-Pseudomonas cephalosporins. Neu, H.C., Labthavikul, P. Antimicrob. Agents Chemother. (1982) [Pubmed]
  3. Comparative in vitro activities of apalcillin and piperacillin against gram-negative bacilli. Fass, R.J., Helsel, V.L. Antimicrob. Agents Chemother. (1984) [Pubmed]
  4. Susceptibility of Eikenella corrodens to penicillin, apalcillin, and twelve new cephalosporins. Goldstein, E.J., Citron, D.M. Antimicrob. Agents Chemother. (1984) [Pubmed]
  5. Tissue concentration and urinary excretion pattern of sulfofluorescein by the rat kidney. Ammer, U., Natochin, Y., Ullrich, K.J. J. Am. Soc. Nephrol. (1993) [Pubmed]
  6. Comparative in vitro activities of cefpiramide and apalcillin individually and in combination. Allan, J.D., Eliopoulos, G.M., Ferraro, M.J., Moellering, R.C. Antimicrob. Agents Chemother. (1985) [Pubmed]
  7. Effects of apalcillin on platelet function in normal volunteers. Gentry, L.O., Wood, B.A., Natelson, E.A. Antimicrob. Agents Chemother. (1985) [Pubmed]
  8. Comparative pharmacokinetics of apalcillin and piperacillin. Lode, H., Elvers, A., Koeppe, P., Borner, K. Antimicrob. Agents Chemother. (1984) [Pubmed]
  9. Pharmacokinetics and bacteriological efficacies of apalcillin and cefpiramide in experimental pneumococcal meningitis. Sato, K., Shelton, S., Nelson, J.D. Antimicrob. Agents Chemother. (1984) [Pubmed]
  10. beta-Lactam resistance in Serratia marcescens: comparison of action of benzylpenicillin, Apalcillin, Cefazolin, and ceftizoxime. Takata, N., Suginaka, H., Kotani, S., Ogawa, M., Kosaki, G. Antimicrob. Agents Chemother. (1981) [Pubmed]
  11. Synergistic activity of apalcillin and gentamicin in a combination therapy in experimental Pseudomonas bacteraemia of neutropenic mice. Fu, K.P., Hetzel, N., Hung, P.P., Gregory, F.J. J. Antimicrob. Chemother. (1986) [Pubmed]
  12. Apalcillin [PC-904]: spectrum of activity and beta-lactamase hydrolysis/inhibition. Barry, A.L., Jones, R.N., Thornsberry, C. Diagn. Microbiol. Infect. Dis. (1985) [Pubmed]
  13. Perioperative antibiotic prophylaxis in bile-duct interventions: results of two prospective randomized studies. Harnoss, B.M., Hirner, A., Dibbelt, H., Häring, R., Rodloff, R., Lode, H. Chemotherapy. (1987) [Pubmed]
  14. Biliary elimination of apalcillin in humans. Brogard, J.M., Arnaud, J.P., Blickle, J.F., Lavillaureix, J. Antimicrob. Agents Chemother. (1984) [Pubmed]
  15. Biliary elimination of apalcillin in cholecystectomized patients. Harnoss, B.M., Harnoss, C.M., Borner, K., Lode, H., Koeppe, P. Chemotherapy. (1985) [Pubmed]
  16. Apalcillin treatment of complicated urinary tract infections. Sharifi, R., Ojeda, L., Lee, M. Urologia internationalis. (1987) [Pubmed]
  17. Biliary elimination of apalcillin: an experimental and clinical study. Brogard, J.M., Arnaud, J.P., Blickle, J.F., Dorner, M., Lautier, F. International journal of clinical pharmacology, therapy, and toxicology. (1986) [Pubmed]
  18. Determination of apalcillin and its metabolites in human body fluids by high-pressure liquid chromatography. Borner, K., Lode, H., Elvers, A. Antimicrob. Agents Chemother. (1982) [Pubmed]
  19. Pharmacokinetics of apalcillin in intensive-care patients: study of penetration into the respiratory tract. Bergogne-Berezin, E., Pierre, J., Chastre, J., Gibert, C., Heinzel, G., Akbaraly, J.P. J. Antimicrob. Chemother. (1984) [Pubmed]
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