Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1NUSOZ (2R,3S,4R,5R)-2,3,4,5- tetrahydroxy-6-[(2S...

Synonyms: FT-0621290

Khatoon, H. et al., Oliveira, J.T. et al., Hassani, M. et al.

Oliveira, Melo, Câmara, Vasconcelos, Beltramini, Machado, Gomes, Pereira, Fernandes, Nunes, Capistrano, Monteiro-Moreira,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on melibiose

Imprecise excision was monitored by selecting for melibiose+ (Mel+) phenotype, which requires only a functioning lacY gene [1].
Mel+ revertants exhibit an array of DNA rearrangements and fall in four main classes, the predominant one being comprised of revertants that have no detectable Mu DNA [1].
Complementation of the above missing functions was achieved by using the Clarke-Carbon plasmids pLC4-5 (LysU LDC) and pLC17-38 (LysU Mel ADI) [2].
Hemagglutination of rabbit erythrocytes was inhibited by either 0.39 mM N-acetyl-neuraminic acid or N-acetyl-D-galactosamin, 12.5 mM D-lactose or D-melibiose, 50 mM D-galactose or raffinose [3].

References

DNA rearrangements associated with reversion of bacteriophage Mu-induced mutations. Khatoon, H., Bukhari, A.I. Genetics (1981) [Pubmed]
Partial characterization of a lysU mutant of Escherichia coli K-12. Hassani, M., Saluta, M.V., Bennett, G.N., Hirshfield, I.N. J. Bacteriol. (1991) [Pubmed]
Purification and physicochemical characterization of a cotyledonary lectin from Luetzelburgia auriculata. Oliveira, J.T., Melo, V.M., Câmara, M.F., Vasconcelos, I.M., Beltramini, L.M., Machado, O.L., Gomes, V.M., Pereira, S.P., Fernandes, C.F., Nunes, E.P., Capistrano, G.G., Monteiro-Moreira, A.C. Phytochemistry (2002) [Pubmed]

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