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Chemical Compound Review

Methacin     2-(2-cyclohexyl-2-hydroxy-2- phenyl...

Synonyms: Spastrex, Atrenyl, Argicillin, Methocidin, Metocidina, ...
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Disease relevance of oxyphenonium

  • We have tested whether the muscarinic antagonists atropine, pirenzepine, oxyphenonium, gallamine, MT-3, himbacine, and 4-DAMP can stimulate ZENK expression so that the drugs' inhibitory effect on myopia development could be explained by an enhanced STOP signal [1].

High impact information on oxyphenonium


Analytical, diagnostic and therapeutic context of oxyphenonium

  • Development of a sensitive radioreceptor assay for oxyphenonium in plasma and urine [4].
  • The masking mechanisms of the bitter taste of propantheline bromide (PB) and oxyphenonium (OB) bromide by native and modified cyclodextrins, saccharides, surfactants, organic acids, nonionic and anionic polymers, and other compounds were investigated with ion selective electrodes [5].


  1. Effects of muscarinic antagonists on ZENK expression in the chicken retina. Bitzer, M., Kovacs, B., Feldkaemper, M., Schaeffel, F. Exp. Eye Res. (2006) [Pubmed]
  2. Radioreceptor assay for oxyphenonium. Ensing, K., de Zeeuw, R.A. European journal of respiratory diseases. Supplement. (1984) [Pubmed]
  3. Effect of local application of oxyphenonium to epididymis on fertility in rats. Ratnasooriya, W.D. Indian J. Exp. Biol. (1982) [Pubmed]
  4. Development of a sensitive radioreceptor assay for oxyphenonium in plasma and urine. Ensing, K., Kluivingh, F., Gerding, T.K., De Zeeuw, R.A. J. Pharm. Pharmacol. (1984) [Pubmed]
  5. Masking mechanisms of bitter taste of drugs studied with ion selective electrodes. Funasaki, N., Uratsuji, I., Okuno, T., Hirota, S., Neya, S. Chem. Pharm. Bull. (2006) [Pubmed]
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