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Chemical Compound Review

Simendan     2-[[4-(4-methyl-6-oxo-4,5- dihydro-1H...

Synonyms: dextrosimendan, Simendan [INN], CHEMBL313136, OR-1259, CHEBI:240651, ...
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Analytical, diagnostic and therapeutic context of Simendan


  1. Pharmacokinetics and pharmacodynamics of simendan, a novel calcium sensitizer, in healthy volunteers. Lilleberg, J., Antila, S., Karlsson, M., Nieminen, M.S., Pentkäinen, P.J. Clin. Pharmacol. Ther. (1994) [Pubmed]
  2. Improved survival with simendan after experimental myocardial infarction in rats. Levijoki, J., Pollesello, P., Kaheinen, P., Haikala, H. Eur. J. Pharmacol. (2001) [Pubmed]
  3. Hemodynamic effects of the novel cardiotonic drug simendan: echocardiographic assessment in healthy volunteers. Lilleberg, J.M., Sundberg, S., Leikola-Pelho, T., Nieminen, M.S. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy. (1994) [Pubmed]
  4. Enatiomeric analysis of simendan by CE with beta-CD as chiral selector compared with CMPA-HPLC. Li, F., Zhang, D., Lu, X., Wang, Y., Xiong, Z. Biomed. Chromatogr. (2004) [Pubmed]
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