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Chemical Compound Review:

KST-1B8855 (1-cyclohexylcyclohexyl) 3...

Synonyms: AR-1B4357, AC1L1M1U, AC1Q60GH

This record was replaced with 6219.

Carlini, E.A., Kagan, G. et al., Page, J.G. et al.

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Disease relevance of 3-diethylaminopropanoic acid (1-cyclohexylcyclohexyl) ester

Treatment of the irritable bowel syndrome with Bentyl (dicyclomine hydrochloride) [1].
Clearly patients like to take frequent treatment for dyspepsia, but symptom control is quite adequate if Merbentyl is given alone [2].

High impact information on 3-diethylaminopropanoic acid (1-cyclohexylcyclohexyl) ester

Synthetic compounds such as triexyphenidyl (Artane), benactizine (Asmosterona), dicyclomine (Bentyl) as well as Datura sp. tea were reported as being used by first and second grade students and by street children of several Brazilian cities [3].

References

Treatment of the irritable bowel syndrome with Bentyl (dicyclomine hydrochloride). Page, J.G., Dirnberger, G.M. J. Clin. Gastroenterol. (1981) [Pubmed]
Comparison of dicyclomine with antacid and without antacid in dyspepsia. Kagan, G., Huddlestone, L., Wolstencroft, P. J. Int. Med. Res. (1984) [Pubmed]
Preliminary note: dangerous use of anticholinergic drugs in Brazil. Carlini, E.A. Drug and alcohol dependence. (1993) [Pubmed]

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