Disease relevance of trichloro-fluoro-methane

• Exposure to 7% oxygen-15% fluorocarbon-11 caused cardiac arrhythmias in all rabbits exposed [1].

High impact information on trichloro-fluoro-methane

• Concomitant with CFC-11 degradation was the near stoichiometric production of fluorodichloromethane (HCFC-21); the production of HCFC-21 was verified by mass spectrometry [2].
• PFPMIE was shown to have instantaneous radiative forcing of 0.65 W m(-2) ppb(-1), which corresponds to a global warming potential on a 100 year time scale of 9000 relative to CO2 and 1.95 relative to CFC-11 [3].
• Fluorocarbon aerosol propellants IV: pharmacokinetics of trichloromonofluoromethane following single and multiple dosing in dogs [4].
• Methanobacterium barkeri was found to catalyze the reductive dehalogenation of trichlorofluoromethane (CFC-11), also known as FREON 11 [5].
• Protein binding of the aerosol propellant, trichloromonofluoromethane, was studied in bovine serum albumin (BSA) solutions using the fluorescent probe technique [6].

Biological context of trichloro-fluoro-methane

• The tropospheric lifetimes of the hydrofluoroethers are estimated to be short tauOH((CF3)2CHOCH3) approximately 100 days, tauOH(CF3CH2OCH2CF3) approximately 80 days, tauOH(CF3CF2CH2OCH3) approximately 20 days, and tauOH(CHF2CF2CH2OCH3) approximately 14 days, and their global warming potentials are small compared to CFC-11 [7].
• When respiratory alterations associated with the inhalation of aerosol propellants were eliminated, it was demonstrated that a ten-minute exposure to trichloromonofluoromethane (Freon 11) at concentrations below 15% never caused death [8].

Associations of trichloro-fluoro-methane with other chemical compounds

• The background concentrations of atmospheric CFC-11 and CFC-12 were monitored to assess their impact on stratospheric ozone depletion and global warming from September 1995 to March 1999 at Kosan, Korea, located at eastern margin of the Asian Continent [9].

References