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Chemical Compound Review

CFCl3     trichloro-fluoro-methane

Synonyms: Refrigerant 11, Halocarbon 11, Propellant 11, Propellent 11, Electro-CF 11, ...
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Disease relevance of trichloro-fluoro-methane


High impact information on trichloro-fluoro-methane


Biological context of trichloro-fluoro-methane

  • The tropospheric lifetimes of the hydrofluoroethers are estimated to be short tauOH((CF3)2CHOCH3) approximately 100 days, tauOH(CF3CH2OCH2CF3) approximately 80 days, tauOH(CF3CF2CH2OCH3) approximately 20 days, and tauOH(CHF2CF2CH2OCH3) approximately 14 days, and their global warming potentials are small compared to CFC-11 [7].
  • When respiratory alterations associated with the inhalation of aerosol propellants were eliminated, it was demonstrated that a ten-minute exposure to trichloromonofluoromethane (Freon 11) at concentrations below 15% never caused death [8].

Associations of trichloro-fluoro-methane with other chemical compounds

  • The background concentrations of atmospheric CFC-11 and CFC-12 were monitored to assess their impact on stratospheric ozone depletion and global warming from September 1995 to March 1999 at Kosan, Korea, located at eastern margin of the Asian Continent [9].


  1. Cardias arrhythmias in hypoxic rabbits during aerosol propellant inhalation. Taylor, G.J. Arch. Environ. Health (1975) [Pubmed]
  2. Dechlorination of trichlorofluoromethane (CFC-11) by sulfate-reducing bacteria from an aquifer contaminated with halogenated aliphatic compounds. Sonier, D.N., Duran, N.L., Smith, G.B. Appl. Environ. Microbiol. (1994) [Pubmed]
  3. Atmospheric lifetime and global warming potential of a perfluoropolyether. Young, C.J., Hurley, M.D., Wallington, T.J., Mabury, S.A. Environ. Sci. Technol. (2006) [Pubmed]
  4. Fluorocarbon aerosol propellants IV: pharmacokinetics of trichloromonofluoromethane following single and multiple dosing in dogs. Niazi, S., Chiou, W.L. Journal of pharmaceutical sciences. (1975) [Pubmed]
  5. Dehalogenation of trichlorofluoromethane (CFC-11) by Methanosarcina barkeri. Krone, U.E., Thauer, R.K. FEMS Microbiol. Lett. (1992) [Pubmed]
  6. Study on the binding of trichloromonofluoromethane by bovine serum albumin using a fluorescent probe technique. Peng, G.W., Chiou, W.L. Pharmacology (1976) [Pubmed]
  7. Study of the OH and Cl-initiated oxidation, IR absorption cross-section, radiative forcing, and global warming potential of four C4-hydrofluoroethers. Oyaro, N., Sellevåg, S.R., Nielsen, C.J. Environ. Sci. Technol. (2004) [Pubmed]
  8. Concentrations of fluoroalkanes associated with cardiac conduction system toxicity. Flowers, N.C., Hand, R.C., Horan, L.G. Arch. Environ. Health (1975) [Pubmed]
  9. Background monitoring and long-range transport of atmospheric CFC-11 and CFC-12 at Kosan, Korea. Kim, J., Oh, S.N., Cho, H.M., Park, M.K., Kim, K.R., Elkins, J.W. Environmental monitoring and assessment. (2001) [Pubmed]
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