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Chemical Compound Review:

Violuric acid 5-hydroxyimino-1,3-diazinane- 2,4,6-trione

Synonyms: AG-H-52651, NSC-56338, NSC56338, LS-16375, CTK5F8329, ...

Colao, M.C. et al., Quaratino, D. et al., Xu, F. et al., Husain, Q., Bartzatt, R., et al.

Colao, Lupino, Garzillo, Buonocore, Ruzzi, Xu, Kulys, Duke, Li, Krikstopaitis, Deussen, Abbate, Galinyte, Schneider, Husain, Bartzatt,

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High impact information on Violuric acid

1-Hydroxybenzotriazole, violuric acid, and N-hydroxyacetanilide are three N-OH compounds capable of mediating a range of laccase-catalyzed biotransformations, such as paper pulp delignification and degradation of polycyclic hydrocarbons [1].
Catalytic rate constants for typical N-OH redox mediators, such as 1-hydroxybenzotriazole (2.6 s(-1)), violuric acid (8.4 s(-1)) and 2,2,6,6-tetramethylpiperidin-N-oxide radical (7.8 s(-1)), were found to be higher than those reported for other high redox potential fungal laccases [2].
Several redox mediators have been reported in the literature, but very few of them are frequently used (e.g., 1-hydroxybenzotriazole, veratryl alcohol, violuric acid, 2-methoxy-phenothiazone) [3].
The molar absorptivity of the violuric acid derivative is calculated to be 31.4 per mol/l per cm [4].
Lcc1 showed high activity in the presence of organic solvents and a high decolourization capacity towards azo, triarylmethane, indigo carmine and anthraquinonic dyes, that could be significantly enhanced in the presence of the redox mediators 1-hydroxybenzotriazole and violuric acid [5].

Associations of Violuric acid with other chemical compounds

Hydrogen-bonding and carbonyl-carbonyl interactions in violuric acid methanol solvate [6].

References

Redox chemistry in laccase-catalyzed oxidation of N-hydroxy compounds. Xu, F., Kulys, J.J., Duke, K., Li, K., Krikstopaitis, K., Deussen, H.J., Abbate, E., Galinyte, V., Schneider, P. Appl. Environ. Microbiol. (2000) [Pubmed]
Production, purification and partial characterisation of a novel laccase from the white-rot fungus Panus tigrinus CBS 577.79. Quaratino, D., Federici, F., Petruccioli, M., Fenice, M., D'Annibale, A. Antonie Van Leeuwenhoek (2007) [Pubmed]
Potential applications of the oxidoreductive enzymes in the decolorization and detoxification of textile and other synthetic dyes from polluted water: a review. Husain, Q. Crit. Rev. Biotechnol. (2006) [Pubmed]
Determination of barbituric acid, utilizing a rapid and simple colorimetric assay. Bartzatt, R. Journal of pharmaceutical and biomedical analysis. (2002) [Pubmed]
Heterologous expression of lcc1 gene from Trametes trogii in Pichia pastoris and characterization of the recombinant enzyme. Colao, M.C., Lupino, S., Garzillo, A.M., Buonocore, V., Ruzzi, M. Microb. Cell Fact. (2006) [Pubmed]
Hydrogen-bonding and carbonyl-carbonyl interactions in violuric acid methanol solvate. Nichol, G.S., Clegg, W. Acta crystallographica. Section C, Crystal structure communications. (2005) [Pubmed]

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