Chemical Compound Review:
AC1LD8JN 5-hydroxy-4-(4- methylsulfonylphenyl)-3...
Synonyms:
5-OH-rofecoxib
- Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism. Zhang, J.Y., Zhan, J., Cook, C.S., Ings, R.M., Breau, A.P. Drug Metab. Dispos. (2003)
- Metabolism of rofecoxib in vitro using human liver subcellular fractions. Slaughter, D., Takenaga, N., Lu, P., Assang, C., Walsh, D.J., Arison, B.H., Cui, D., Halpin, R.A., Geer, L.A., Vyas, K.P., Baillie, T.A. Drug Metab. Dispos. (2003)
- Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques. Baillie, T.A., Halpin, R.A., Matuszewski, B.K., Geer, L.A., Chavez-Eng, C.M., Dean, D., Braun, M., Doss, G., Jones, A., Marks, T., Melillo, D., Vyas, K.P. Drug Metab. Dispos. (2001)