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Chemical Compound Review

AC1O745K     2-[ (3S,5S,6R,7S,8E,10R,11R,12Z,14 E)-6...

Synonyms:
 
 
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Disease relevance of nchembio790-comp21

 

High impact information on nchembio790-comp21

 

Analytical, diagnostic and therapeutic context of nchembio790-comp21

References

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  2. A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma. Ronnen, E.A., Kondagunta, G.V., Ishill, N., Sweeney, S.M., Deluca, J.K., Schwartz, L., Bacik, J., Motzer, R.J. Investigational new drugs. (2006) [Pubmed]
  3. 17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models. Burger, A.M., Fiebig, H.H., Stinson, S.F., Sausville, E.A. Anticancer Drugs (2004) [Pubmed]
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  9. Measurement of the novel antitumor agent 17-(allylamino)-17-demethoxygeldanamycin in human plasma by high-performance liquid chromatography. Agnew, E.B., Wilson, R.H., Grem, J.L., Neckers, L., Bi, D., Takimoto, C.H. J. Chromatogr. B Biomed. Sci. Appl. (2001) [Pubmed]
  10. Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts. Eiseman, J.L., Lan, J., Lagattuta, T.F., Hamburger, D.R., Joseph, E., Covey, J.M., Egorin, M.J. Cancer Chemother. Pharmacol. (2005) [Pubmed]
 
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