MeSH Review:
Focal Adhesions
- Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Sefton, B.M., Hunter, T., Ball, E.H., Singer, S.J. Cell (1981)
- Suppression of tumor growth and metastasis in Mgat5-deficient mice. Granovsky, M., Fata, J., Pawling, J., Muller, W.J., Khokha, R., Dennis, J.W. Nat. Med. (2000)
- Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis. Levkau, B., Herren, B., Koyama, H., Ross, R., Raines, E.W. J. Exp. Med. (1998)
- Focal adhesion kinase in netrin-1 signaling. Ren, X.R., Ming, G.L., Xie, Y., Hong, Y., Sun, D.M., Zhao, Z.Q., Feng, Z., Wang, Q., Shim, S., Chen, Z.F., Song, H.J., Mei, L., Xiong, W.C. Nat. Neurosci. (2004)
- Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin. Murphy-Ullrich, J.E., Lightner, V.A., Aukhil, I., Yan, Y.Z., Erickson, H.P., Höök, M. J. Cell Biol. (1991)
- Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Foo, S.S., Turner, C.J., Adams, S., Compagni, A., Aubyn, D., Kogata, N., Lindblom, P., Shani, M., Zicha, D., Adams, R.H. Cell (2006)
- Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Xie, Z., Sanada, K., Samuels, B.A., Shih, H., Tsai, L.H. Cell (2003)
- Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Littlewood Evans, A., Müller, U. Nat. Genet. (2000)
- Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. Bai, J., Uehara, Y., Montell, D.J. Cell (2000)
- Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Nobes, C.D., Hall, A. Cell (1995)
- Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions. Black, D.S., Bliska, J.B. EMBO J. (1997)
- Stimulation of beta1 integrin down-regulates ICAM-1 expression and ICAM-1-dependent adhesion of lung cancer cells through focal adhesion kinase. Yasuda, M., Tanaka, Y., Tamura, M., Fujii, K., Sugaya, M., So, T., Takenoyama, M., Yasumoto, K. Cancer Res. (2001)
- PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation. Park, M.J., Kim, M.S., Park, I.C., Kang, H.S., Yoo, H., Park, S.H., Rhee, C.H., Hong, S.I., Lee, S.H. Cancer Res. (2002)
- Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells. Lacerda, H.M., Pullinger, G.D., Lax, A.J., Rozengurt, E. J. Biol. Chem. (1997)
- Progesterone induces focal adhesion in breast cancer cells MDA-MB-231 transfected with progesterone receptor complementary DNA. Lin, V.C., Ng, E.H., Aw, S.E., Tan, M.G., Ng, E.H., Bay, B.H. Mol. Endocrinol. (2000)
- Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation. Hall, C.L., Yang, B., Yang, X., Zhang, S., Turley, M., Samuel, S., Lange, L.A., Wang, C., Curpen, G.D., Savani, R.C., Greenberg, A.H., Turley, E.A. Cell (1995)
- Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes. Carter, W.G., Ryan, M.C., Gahr, P.J. Cell (1991)
- Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Schlaepfer, D.D., Hanks, S.K., Hunter, T., van der Geer, P. Nature (1994)
- Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Amano, M., Chihara, K., Kimura, K., Fukata, Y., Nakamura, N., Matsuura, Y., Kaibuchi, K. Science (1997)
- The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Cowan, C.A., Henkemeyer, M. Nature (2001)
- Monensin inhibits initial spreading of cultured human fibroblasts. Pizzey, J.A., Bennett, F.A., Jones, G.E. Nature (1983)
- The molecular mystery of neuronal migration: FAK and Cdk5. Nikolic, M. Trends Cell Biol. (2004)
- Signaling complexes: biophysical constraints on intracellular communication. Bray, D. Annual review of biophysics and biomolecular structure. (1998)
- Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Di Paolo, G., Pellegrini, L., Letinic, K., Cestra, G., Zoncu, R., Voronov, S., Chang, S., Guo, J., Wenk, M.R., De Camilli, P. Nature (2002)
- Regulation of a neuronal form of focal adhesion kinase by anandamide. Derkinderen, P., Toutant, M., Burgaya, F., Le Bert, M., Siciliano, J.C., de Franciscis, V., Gelman, M., Girault, J.A. Science (1996)
- Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. Kinoshita, M., Kumar, S., Mizoguchi, A., Ide, C., Kinoshita, A., Haraguchi, T., Hiraoka, Y., Noda, M. Genes Dev. (1997)
- Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., Yamada, K.M. Science (1998)
- Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Ishibe, S., Joly, D., Liu, Z.X., Cantley, L.G. Mol. Cell (2004)
- Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Kissil, J.L., Wilker, E.W., Johnson, K.C., Eckman, M.S., Yaffe, M.B., Jacks, T. Mol. Cell (2003)
- Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation. Denker, S.P., Huang, D.C., Orlowski, J., Furthmayr, H., Barber, D.L. Mol. Cell (2000)
- RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells. Bacon, K.B., Szabo, M.C., Yssel, H., Bolen, J.B., Schall, T.J. J. Exp. Med. (1996)
- Isolation and partial characterization of human platelet vinculin. Rosenfeld, G.C., Hou, D.C., Dingus, J., Meza, I., Bryan, J. J. Cell Biol. (1985)
- Fibroblast adhesion to RGDS shows novel features compared with fibronectin. Streeter, H.B., Rees, D.A. J. Cell Biol. (1987)
- Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. Fuortes, M., Jin, W.W., Nathan, C. J. Cell Biol. (1993)