Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Eufans (2-methoxyphenyl) 2-[2-[1-methyl-5-(4...

Synonyms: Artromed (TN), SureCN24555, MED 15, AG-H-52420, CHEMBL1766570, ...

Tubaro, E. et al., Arrigoni-Martelli, E., Caruso, A. et al.

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Disease relevance of MED 15

Experimental allergic encephalomyelitis in guinea-pigs was not affected by ST 679 [1].

High impact information on MED 15

Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin [2].
Amtolmetin guacyl (CAS 873344-06-7, MED 15) is a non-steroidal anti-inflammatory drug (NSAID) which has shown gastroprotective effects attributable to capsaicin receptor stimulation through the presence of a vanillic moiety in its molecular structure [3].

References

Profile of activity of a new anti-inflammatory agent, ST 679 (MED 15). Arrigoni-Martelli, E. Drugs under experimental and clinical research. (1990) [Pubmed]
Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin. Caruso, A., Cutuli, V.M., De Bernardis, E., Attaguile, G., Amico-Roxas, M. Drugs under experimental and clinical research. (1992) [Pubmed]
Anti-inflammatory and antiplatelet effects of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. Tubaro, E., Belogi, L., Mezzadri, C.M. Arzneimittel-Forschung. (2001) [Pubmed]

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