Disease relevance of NSC83567

• Discovery of novel N-phenylglycine derivatives as potent and selective beta(3)-adrenoceptor agonists for the treatment of frequent urination and urinary incontinence [1].

High impact information on NSC83567

• This study evaluated and compared the contributions to dentin adhesive bonding of three N-phenylglycine analogues with electron-withdrawing substituents on the aromatic ring [2].
• In the second step, the amount of the N-compound--either N-phenylglycine (NPG), N-methyl-N-phenylglycine (NMNPG), or N-phenyl-beta-alanine (NPBA)--was varied in acetone from 0 mol/L through 5 x 10(-1) mol/L in seven steps [3].
• Previous studies have shown that sequential use of aqueous FO (ferric oxalate containing a small concentration of HNO3), acetone solutions of NPG (N-phenylglycine), and PMDM (the reaction product of pyromellitic dianhydride and 2-hydroxyethylmethacrylate) yields strong adhesive bonding of composite resins to both dentine and enamel [4].

Associations of NSC83567 with other chemical compounds

• Use of acidic solutions containing glycine or N-phenylglycine was found to give bonds of high strength to both dentin and enamel [5].
• Dentin surfaces were pretreated according to several variations of a three-step bonding protocol involving sequential application of 6.8 w/o ferric oxalate in 2.5 w/o HNO3, N-phenylglycine in acetone, and an experimental bonding resin before placement of a chemically cured composite restorative material [6].
• This research was designed to study the effect of water or carboxylic acid monomer on the polymerization of 2-hydroxyethyl methacrylate (HEMA) in order to understand the bonding mechanism of dentin bonding systems using N-phenylglycine (NPG) [7].

Analytical, diagnostic and therapeutic context of NSC83567

• We used gas chromatography mass spectrometry to identify PAA in rat liver, as well as N-(hydroxyphenyl)glycine, N-phenylglycine, 3-(pheylamino)lactic acid, and 3-(hydroxyphenylamino)-lactic acid in rat urine [8].

References